Successful reconstruction of the aortic valve requires the preliminary creation of the anatomical design of its image, which includes a set of parameters of the valves of a particular valve. Errors in operation at the stage of design of valve components are fraught with subsequent dysfunction. In the present, the optimal sizes of the aortic root and the valves of the aortic valve were evaluated and the presence and values of correlations between them were determined. Statistically significant anatomical and functional correlations of morphometric characteristics of aortic root structures were revealed to achieve the optimal level of their correspondence in autologous grafts during surgical correction of the aortic valve. The main morphometric parameters of the aortic root were analyzed on the example of 54 samples obtained post mortem from patients whose death occurred from causes not associated with heart disease. The cases with aortic valve disease were excluded from the study. The following parameters were evaluated: circumference of the ventriculo-arterial junction; circumference of the sinuses of Valsalva; circumference of the sinutubular junction. Separately, for each of the three cusps of the native aortic valve, were evaluated: the length of the free edge of the cusp (L1); the length of the junction of the leaflet and the fibrous ring of the aortic valve (L2); leaflet height (A); intercommissural distance (IC). A search was made for the correlation between the size of the valves and the parameters of the circumference of the aortic root at the level of the ventriculo-arterial junction, of the sinuses of Valsalva and of sinutubular junction. A significant presence of a correlations was found between all parameters of the aortic valve cusps and the length of the aortic circumference at the level of the ventriculo-arterial junction, of the sinuses of Valsalva and sinutubular junction (r>0.6 for IC, L1, L2 and r>0.5 for A at p<0,01). The data obtained by correlation analysis make it possible to standardize the design of the autograft of the aortic valve, thereby ensuring the best coaptation of the valves and, as a result, the function of the aortic valve.
It was analyzed the results of treatment of 152 patients who underwent heart valve surgery. Depending on cardiopulmonary bypass (CPB) duration patients were divided into 4 groups: the 1st--up to 90 min, the 2nd--90-120 min, the 3rd--120-180 min, the 4th--more than 180 min. Severity of initial comorbidities was comparable in all groups. It was revealed that CPB duration effects on intraoperative blood loss, incidence of acute renal failure, encephalopathy, use of inotropic and angiotonic support (p<0.05). Accession of CPB duration was associated with increased number of postoperative complications in all groups (p<0.05). "Critical periods" of CPB for every type of postoperative complications are defined.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.