The indigenous population of the North can efficiently preserve health and vital activity, and reproduce new generations under extreme climatic and geographic conditions due to peculiar way of life, mental features, rituals, regimes of work and rest, social and cultural traditions. Of great importance are also the clothes which are favorable for keeping heat and self-cleaning, some psycho-therapeutic factors (rituals of shamanism), animal food and vegetables. The phenotype of the adaptation reserves of an organism, northern type of metabolism, dominance of the right brain hemisphere play a great role, so does the adaptation of national mentality to the harmony of inner human state with the extreme environmental conditions of high latitudes.
The enrichment by highly information load of the school educational process, which leads in severe environment to psycho-emotional stress, confirms the necessity of studying the psycho-emotional and physiological stability of the senior schoolboys to information educational stress in rugged climate/geographic regions of Siberia. Observed were the 110 teenagers, the inhabitants of Novosibirsk, the students of 9 th-10 th classes of the special lycée. Clinical, psychological, psychophysiological, biochemical and hormonal methods of observation were used. It was shown that efficiency of the modern information-enriched educational process defines a complex of individual adaptive characteristics of an organism, including lateral phenotype of the prevalence of cerebral hemispheres, the stability of psychophysiological response, minimization of painful reaction to sharp changes of the factors of nature-meteosensitivity, and also the belonging to chronotypes (morning or evening). These features form the basis of stability of the young organism to the educational information stress and to the action of rugged climate-meteorological and biorhytmological factors, aggravating this stress.
В последнее время в современной литературе появляется все больше публикаций, свидетельствующих о том, что важным компонентом спонтанных срочных родов у человека является воспалительный процесс. В 1999 г. вышла работа A. Thompson и соавт. [1], в которой показана лейкоцитарная инфильтрация миометрия во время срочных самопроизвольных родов, что позволило авторам трактовать роды как воспалительный процесс. Было показано, что во время срочных родов в нижнем сегменте миометрия количество нейтрофилов увеличивается в 196 раз, макрофагов-в 7,3 раза, Т-лимфоцитов-в 15 раз [1]. Эти изменения начинаются в предродовый период. Лейкоцитарная инфильтрация выявлена как в нижнем, так и в верхнем сегментах миометрия. Был сделан вывод, что лейкоциты, инфильтрирующие миометрий при спонтанных срочных родах, играют фундаментальную роль в их индукции и сопровождении. В последующие годы эта гипотеза была неоднократно подтверждена и дополнена. К настоящему времени она из гипотезы перешла в непреложный факт [2, 3].
The cytokines' levels of pro-inflammatory and anti-inflammatory activity, levels of lactoferrin, of the circulating immune complexes and the level of antibodies to antigens of the native deoxyribonucleic acid (DNA) are investigated. The purpose of investigation was to study the pathogenic features of clinical course of chronic lambliasis invasia at teenagers. The statistically significant hypercitokinemia owing to the pro-inflammatory and anti-inflammatory cytokines with the highest concentration of IL-1β, IL-4, the high level of lactoferrin-protein of acute phase, the occurrence of markers of cellular damage, the high level of immune complexes and the stimulation of humoral link of immune system, the high level of antibodies to the antigen of native DNA, are registered. The obtained data may be used as additional diagnostic criteria of lambliasis invasia at teenagers.
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