The objective of this research was to study the effectiveness and safety of proceduralist given sedation in pediatric flexible bronchoscopy. Flexible bronchoscopy was performed in all 267 patients. All patients received midazolam and/or ketamine. The median (interquartile range [IQR]) age of the studied population was 16 (18) months. The indication of bronchoscopy varied. The mean ± standard deviation (SD) dose of midazolam was 0.109 (0.03) mg/kg and that of ketamine was 1.17 (0.43) mg/kg. We observed minor side effects of procedural sedation. All patients underwent procedure successfully. Flexible bronchoscopy in children can be safely performed under sedation using a combination of midazolam and ketamine.
Introduction: Outcome of paediatric PAH has not been studied in our population. Current study aimed to see the outcome of children over a study period of one year who were diagnosed as pulmonary arterial hypertension.
Material and Methods:Study was done on all children 0-15 years age diagnosed with PAH on Transthoracic Echocardiography with systolic pulmonary artery pressure (sPAP) of >35 mmHg. Only Group 1 PAH (WHO) were included and were followed for 1 year. Various clinical and echocardiographic variables affecting outcome were noted.Results: Total number of PAH cases were 40. Mean age at the time of diagnosis was 7.3 months. 23 (57.5%) of the PAH patients were females whereas 17 (42.5%) were males. Idiopathic PAH constituted 42.5% of the study group, whereas 50% of the PAH cases were associated with CHD. 7.5% cases were diagnosed as PPHN Out of the total of 40 cases studied 10 patients died representing 25% mortality over 1 year.
Conclusion:Paediatric PAH is associated with high mortality in our population.Those having Right heart failure and Right Ventricular Dysfunction need close follow up.
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