Purpose The purpose of this paper is to utilise a “Wuli-Shili-Renli (WSR)” system approach to create models for complex smart building energy management and evaluate the establishment of a building energy management platform. Design/methodology/approach The complexity and diversity of the data and demands of the energy management platform mean that it is necessary to analyse comprehensively. This paper uses a WSR system approach to handle, and optimise, the relationship between demands and participants and improve the whole platform. Then, this paper establishes comprehensive evaluation models to analysis the current energy management platforms by using the best integration platform as the baseline. Findings The WSR conceptual model clarifies the relationship between the elements and elements of the energy management platform clearly and provides the appropriate analytical methods with which to resolve key platform construction issues. The comprehensive evaluation based on a WSR system approach can take into account the systematic effect, so it is more accurate. Research limitations/implications The correlation degree between the layers of the energy management platform is rarely reflected. Originality/value This paper improves the modelling method used in the WSR system approach and demonstrates that the comprehensive evaluation based on the WSR system approach analyses the energy management platform for public buildings in a synthetic approach.
Reversine (Rev) has been used for the treatment of a number of cancers. However, there have been no previous reports for the use of Rev for gastric cancer (GC). The aim of the present study was to investigate the effect of Rev on cell proliferation, migration, invasion and cell apoptosis in human GC cells and TTK expression. Cell Counting Kit-8 and colony formation were used to assess cell proliferation. Wound healing and Transwell assays were performed to examine cell migration and invasion, respectively. Cell apoptosis was measured using TUNEL staining and western blotting. Reverse transcription-quantitative PCR and western blotting were performed to determine TTK expression in AGS and NCI-N87 GC cells. Rev treatment inhibited the viability of the two GC cells lines in a dose-dependent manner and suppressed their capacities of clone formation, migration and invasion. Rev-treated cells exhibited reduced matrix metalloproteinase (MMP)2/9 expression and increased apoptosis compared with those in control cells. In addition, expression of the anti-apoptotic protein Bcl-2 was significantly decreased, whilst the expression levels of the pro-apoptotic factors Bax and cleaved-caspase-3/9 were increased by Rev treatment compared with that in the control group that were not treated with Rev. In addition, TTK protein expression was decreased in cells treated with Rev compared with that in untreated cells. However, overexpression of TTK significantly reversed the aforementioned effects of Rev in GC cells. These results suggest that Rev may inhibit the proliferation, invasion and migration of GC cells whilst inducing cell apoptosis by suppressing TTK expression. Therefore, Rev may confer potential properties as a therapeutic anti-cancer agent. Additionally, TTK may serve as a molecular target for the treatment of gastric cancer.
This study examines a new methodology to predict the final seismic mortality from earthquakes in China. Most studies established the association between mortality estimation and seismic intensity without considering the population density. In China, however, the data are not always available, especially when it comes to the very urgent relief situation in the disaster. And the population density varies greatly from region to region. This motivates the development of empirical models that use historical death data to provide the path to analyze the death tolls for earthquakes. The present paper employs the average population density to predict the final death tolls in earthquakes using a case-based reasoning model from realistic perspective. To validate the forecasting results, historical data from 18 large-scale earthquakes occurred in China are used to estimate the seismic morality of each case. And a typical earthquake case occurred in the northwest of Sichuan Province is employed to demonstrate the estimation of final death toll. The strength of this paper is that it provides scientific methods with overall forecast errors lower than 20 %, and opens the door for conducting final death forecasts with a qualitative and quantitative approach. Limitations and future research are also analyzed and discussed in the conclusion.
Abstract-At present, there is a difficult situation in promoting and applying Building Information Modeling (BIM) in China. Many Chinese scholars made summaries of a range of obstacles in different practices; however, there is no clear guidance and effective strategy from which they can learn and enhance their capacity in using BIM. In this paper, we analyze the BIM application in China and seek to present what is the most reasonable strategy, which is inevitably impeded by the result of the existence of externalities. Moreover, analysis of the obstacles and establishments of Dynamic Game Model based on complete information are firstly proposed among enterprises and government. The overall aim of the Model is to find the relations between government and participants, and to discover the practice method in BIM application. It is concluded that the government with the most powerful influence on the promotion of BIM application is expected to formulate corresponding policies to improve BIM's development. Notably, since the Economic Efficiency, the main influential factor for BIM applications, leads economic incentive policies to be in charge of popularizing and deepening BIM applications, the degree of motivation becomes a key element to promote BIM technology. Therefore, we can rationally figure out that the government should strengthen the BIM technology research and its development in order to solve the problems or obstacles of BIM applications.
In order to promote the sustainable development of architectural industrialization, it is necessary to evaluate its development level, identify the development status and key restricting factors, and achieve the effect of “promoting the development by evaluation”. However, the existing studies are mostly limited to the scope of provinces and cities, and there are few studies on the construction industrialization of an economic circle as a whole. Therefore, this paper locates the research within the scope of the region, constructs the evaluation model of the sustainable development level of the regional construction industrialization, and selects the Beijing-Tianjin-Hebei region as a case study. The research shows that the sustainable development level of construction industrialization in the Beijing-Tianjin-Hebei region is in the middle level, which needs to be improved from the aspects of economic support, technological innovation, and management. This paper provides a reasonable reference for how to evaluate and better promote the sustainable development of regional construction industrialization.
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