Background
Hyperuricemia is one of the important risk factors for gout, arteriosclerosis, cardiovascular and cerebrovascular disease. Lactobacillus has attracted much attention due to its role in the regulation of intestinal function and tumor resistance, but its ability to reduce uric acid is unclear. Pickles are a traditional fermented food rich in lactic acid bacteria (LAB).
Results
LAB strains were isolated from 18 pickles and their tolerance to acid bile salts, trypsin, pepsin were evaluated after screening by nucleoside degradation. 16S rDNA sequence analysis was used to identify LAB strains. Furthermore, we established rat model of hyperuricemia and demonstrated that Lactobacillus could alleviate hyperuricemia and reduce kidney injury.
Conclusion
This study suggests that microecological treatment with Lactobacillus represents a feasible option for patients with chronic hyperuricemia.
The openings of an enclosure allow natural ventilation and light ingress but also act as a point of entry for noise of the whole structure. In this paper, the active control of the sound transmitted through a small opening in a wall formed by two infinitelylarge baffles is investigated up to 4000 Hz. Based on an analytical model developed with the modal expansion method, the effects of different secondary source and the error sensor strategies are compared numerically for different types of primary sound fields. The upper limit frequency of effective control is found to be determined by the eigen frequency of the acoustic modes of the opening. Experimental results with an opening of 6 cm by 6 cm on a 31.8 cm thick wall agree well with the numerical results.The upper limit frequency of effective control is found to be 2750 Hz for a singlechannel system and 3900 Hz for a 4-channel system with more than 10 dB noise reduction. It is concluded that implementing active control in small openings with appropriate secondary source and error sensing strategy can extend the frequency range of control significantly, so that the active control systems can be applied to more noise control scenarios which have both noise reduction and ventilation requirements in the middle to high frequency range.
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