Since the 21st century, there is no doubt that the importance of artificial intelligence has been highlighted in many fields, among which the memristor-based artificial neural networks technology is expected...

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The ideal magnetic flux-controlled memristor was introduced into a four-dimensional chaotic system and combined with fractional calculus theory, and a novel four-dimensional commensurate fractional-order system was proposed and solved using the Adomian decomposition method. The system orders, parameters, and initial values were studied as independent variables in the bifurcation diagram and Lyapunov exponents spectrum, and it was discovered that changing these variables can cause the system to exhibit more complex and rich dynamical behaviors. The system had an offset boosting, which was discovered by adding a constant term after the decoupled linear term. Finally, the results of the numerical simulation were verified through the use of analog circuits and FPGA designs, and a control scheme for the system circuit was also suggested.

Aim: To investigate whether silibinin impacts diabetic periodontitis (DP) via mitochondrial regulation. Materials and Methods:In vivo, rats were divided into control, diabetes, DP and DP combined with silibinin groups. Diabetes and periodontitis were induced by streptozocin and silk ligation, respectively. Bone turnover was evaluated by microcomputed tomography, histology and immunohistochemistry. In vitro, human periodontal ligament cells (hPDLCs) were exposed to hydrogen peroxide (H 2 O 2 ) with or without silibinin. Osteogenic function was analysed by Alizarin Red and alkaline phosphatase staining. Mitochondrial function and biogenesis were investigated by mitochondrial imaging assays and quantitative polymerase chain reaction. Activator and lentivirus-mediated knockdown of peroxisome proliferator-activated receptor gamma-coactivator 1-alpha (PGC-1α), a critical regulator of mitochondria biogenesis, was used to explore the mitochondrial mechanisms.Xiaoyu Sun, Yifan Ping, and Xumin Li contributed equally to this study.