Most of periapical lesions usually result from microbial infection with oral microorganisms originating from the degenerated pulp tissue. These lesions are commonly painless and incidentally found on routine radiographic examinations. Treating these cases using non-surgical root canal is the fruit of the innovative techniques, tools and root medicaments as well as the tendency toward minimally invasive treatment. The healing process of the infected area is conditioned by a proper diagnosis, a treatment that follows good clinical practice under aseptic environment including cleaning, shaping and root filing. The aim of the present clinical case report was to report non-surgical healing of a periapical lesion of endodontic origin associated with maxillary left central incisor, observed over a period of 2 years.
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