We describe a low-loss single-mode waveguide in planar light-wave circuit (PLC) glass doped with boron and phosphorus, which is more difficult to write than pure-silica glass. The written waveguide has a rectangular core, a symmetric near-field pattern, and a propagation loss of 0.35 dB/cm. The loss that originates from the mode-field mismatch between the mode-field diameters of the written and the PLC waveguides is less than 0.1 dB/point. In addition, we successfully connected PLC waveguides with a 500-microm-long waveguide written with a laser. The laser-written waveguide can flexibly connect PLC waveguides with a low coupling loss.
Abstractl-Lactate, traditionally considered a metabolic waste product, is increasingly recognized as an important intercellular energy currency in mammals. To enable investigations of the emerging roles of intercellular shuttling of l-lactate, we now report an intensiometric green fluorescent genetically encoded biosensor for extracellular l-lactate. This biosensor, designated eLACCO1.1, enables cellular resolution imaging of extracellular l-lactate in cultured mammalian cells and brain tissue.
We propose a technique for multiplexing fibre Bragg grating (FBG) sensors with the same
Bragg wavelength. We have already developed a technique for the synthesis of an optical
coherence function, in which we can select one signal among various reflections along an
optical path in an interferometer. By applying the technique, the reflection spectrum
of each FBG in arrayed FBGs can selectively be obtained, even if the array is
composed of FBGs with the same Bragg wavelength. In this paper, we first describe
the principle of the proposed system, and then show the experimental results.
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