Arid and semiarid lowland areas of central Asia are largely dependent on fluvial water originating from the Tian Shan. Mountain glaciers contribute significantly to runoff, particularly in summer. With global warming, the total glacier area in the Kunma Like River catchment declined by 13.2% during 1990–2007. For future water resources, it is essential to quantify the responses of hydrologic processes to both climate change and shrinking glaciers in glacierized catchments, such as the headwaters of the Tarim River. Thus, a degree-day glacier melt algorithm was integrated into the macroscale hydrologic Variable Infiltration Capacity model (VIC). Good results were obtained for monthly runoff simulations in the Kunma Like River catchment, which suggest that the extended VIC has acceptable performance. Because of increased precipitation and air temperature, annual runoff in the catchment has increased by about 4.07 × 108 m3 decade−1 during 1984/85–2006/07. Under the assumption of the same climatic conditions, sensitivity analyses indicated that annual and summer river runoff volumes would decrease by 9.3% and 10.4%, respectively, for reductions in glacier area of 13.2%. The variation coefficient of annual runoff also increased because of shrinking glaciers. Runoff scenarios for warmer future climate and various deglaciation situations suggest that reductions in glacier area by >30% will likely produce less meltwater in summer and river runoff will decline. Consequently, the annual total discharge of the Kunma Like River is projected to decrease by 2.8%–19.4% in the 2050s scenario because of glacier shrinking.

In this paper, we enhance physical layer security for downlink heterogeneous networks (HetNets) by using friendly jammers and full-duplex users. The jammers are selected to transmit jamming signal if their interfering power on the scheduled users is below a threshold, meanwhile the scheduled users confound the eavesdroppers using artificial noise by fullduplexing. Using the tools of stochastic geometry, we derive the expressions of connection probability and secrecy probability. In particular, the locations of active jammers are modeled by a modified Poisson hole process (PHP). Determining the jammer selection threshold is further investigated for connection probability maximization subject to the security constraints. A greedy algorithm is proposed to efficiently solve this problem. The accuracy of the theoretical analysis and the efficiency of the proposed algorithm are evaluated by numerical simulations.Index Terms-Physical layer security, heterogeneous networks, full-duplex, stochastic geometry, Poisson hole process.U,t \u0 P U h ui,u0 D −α ui,u0 and I J = zi∈Φ s J P J h zi,u0 D −α zi,u0 . N S and N 0 represent the residual self-interference and the thermal noise, respectively. In this paper, we assume a linear residual self-interference performance as N S = βP U , where β is the SIC capacity.

Background: Mitomycin (MMC) has been frequently used as the compound for intravesical treatment. The relatively new pyrimidine analog gemcitabine (GEM) has exhibited anticancer effect on various solid cancers, such as the advanced bladder cancer. In this study, the GEM and MMC in treating non-muscle invasive bladder cancer (NMIBC) cases was compared through systemic review. Methods: In accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement, the electronic databases, including Embase, PubMed, Chinese biomedicine literature database, the Cochrane Library, the National Institute for Health and Clinical Excellence, NHS Evidence, Chinese technological periodical full-text database, and Chinese periodical full-text database, were systemically reviewed from inception to October 2018. Then, the RevMan 5.0 software was applied for data analysis. Five randomized controlled trials (RCTs) involving a total of 335 patients were included. Results: For MMC group, the recurrence rate in the mitomycin arm increased compared with that in GEM group (OR = 0.44 95% CI [0.24, 0.78]), and the difference was statistically significant between the two groups. GEM was associated with reduced incidence of chemical cystitis compared with that of MMC (OR = 0.23 95% CI [0.12, 0.44]). Differences in hematuria (OR = 0.46 95% CI [0.16, 1.31]), skin reaction (OR = 0.49 95% CI [0.14, 1.70]) and liver and kidney function damage (OR = 0.51 95% CI [0.09, 2.85]) displayed no statistical significance between the two groups. Conclusion: Findings in our study demonstrate the superior efficacy of GEM over MMC in reducing the relapse rate among NMIBC patients following transurethral resection (TUR). In addition, GEM is associated with reduced local toxic effects on the bladder compared with those of MMC. However, more future studies are needed to examine GEM safety when used as the monotherapy or polytherapy for bladder patients. More RCTs with high quality are also required to validate our findings due to the limitations of the current meta-analysis.

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