Sclerosing stromal tumor (SST) is a rare benign ovarian neoplasm classified as a type of sex cord stromal tumor that occurs predominantly in young patients. Several reports have described the US, CT and MR features of SST, but there have been no reports of a bilateral calcified SST in a child. We present a case of a bilateral SST of the ovary with calcification in a 12-year-old premenarchal girl and describe the US, CT, MR and pathological findings.
Background and aim:Breast cancer is the second most common malignancy in Korean women. Fine needle aspiration cytology (FNAC) has been used as the first-line pathological modality; however, use of core needle biopsy (CNB) is on the increase. FNAC is a cost effective, less invasive and rapid method for evaluation of breast lesions. The limitations of FNAC, such as high false negative rates and equivocal results restrict its use. The aim of this study is to evaluate FNAC as a diagnostic tool in comparison with CNB by matching corresponding excision specimens. Methods: From May, 2003 to April, 2008, 753 cases of FNAC, 331 cases of CNB, and 98 cases of combined FNAC and CNB were collected. Diagnoses with FNAC and CNB were compared with excision. Results: Sensitivity, specificity, and diagnostic accuracy of FNAC were 93.8%, 80.8%, and 90.1%, respectively. Those of CNB were 92.1%, 90.9%, and 92.3%, and combined FNAC and CNB, 100%, 77.8%, and 98.0%. There were no false positive cases in either the FNAC or the CNB group. False negative rates were 6.2% in FNAC and 9.9% in CNB. Sampling error was the cause of error or a false negative result in all FNAC samples, and all but one CNB sample. Diagnostic accuracy of FNAC was superior to that of CNB for lesions between 1 cm and 2 cm. Conclusions: Our data suggest that FNAC is an accurate and reliable first line diagnostic tool for evaluation of breast lesions when compared with core biopsy.
Nonalcoholic steatohepatitis (NASH), one of the NAFLDs (nonalcoholic fatty liver diseases), is regarded as a hepatic manifestation of metabolic syndrome. NASH can progress to cirrhosis, and possibly to hepatic malignancy. Currently, liver biopsy is the only reliable method of assessing the presence or absence of NASH and the stage of fibrosis. The finding of steatosis with evidence of hepatocyte injury such as inflammation, ballooning, degeneration, and/or fibrosis, is generally essential for making a diagnosis of NASH. However, its diagnostic criteria have not yet been established. The pathologic findings of NASH and related diseases, and the grading system currently in use are reviewed herein.
The authors report a rare case of Horner syndrome in a patient with neurofibromatosis type 1 (NF-1). A 31-year-old man visited the clinic with drooping left eyelid. The physical examination revealed ptosis of the left eyelid, miotic pupil, facial anhidrosis, and several skin masses on the chest. The radiological examination of the chest demonstrated a well-defined left posterior mediastinal mass close to the vertebral bodies of the upper thoracic spine at the level of T1-T5. The masses of mediastinum and skin were totally removed. They were diagnosed as neurofibromas. Neurofibromatosis type 1 was diagnosed. To the best of my knowledge, this is a rare case of a patient with NF-1 who presented with Horner syndrome. Clinicians should be vigilant on the possibility of Horner syndrome in patients with NF-1.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.