Polycyclic aromatic derivatives can trap 1 O 2 to form endoperoxides (EPOs) for O 2 storage and as sources of reactive oxygen species.H owever,t hese materials suffer from structural amorphism, which limit both practical applications and fundamental studies on their structural optimization for O 2 capture and release.Metal-organic frameworks (MOFs) offer advantages in O 2 binding,such as clear structure-performance relationships and precise controllability.Herein, we report the reversible binding of O 2 is realized via the chemical transformation between anthracene-based and the corresponding EPO-based MOF.Itisshown that anthracene-based MOF,the framework featuring linkers with polycyclic aromatic structure,c an rapidly trap 1 O 2 to form EPOs and can be restored upon UV irradiation or heating to release O 2 .Furthermore,we confirm that photosensitizer-incorporated anthracene-based MOF are promising candidates for reversible O 2 carriers controlled by switching Vis/UV irradiation.Endoperoxides (EPOs) have interesting photochemical and thermodynamic properties. [1] Their potential applications for reversible oxygen storage and as chemical sources of reactive oxygen species,h ave made these compounds the focus of many fundamental investigations. [2] Many polycyclic aromatic derivatives could trap the singlet oxygen ( 1 O 2 )t of orm EPOs. [3] EPOs exhibit the exceptional performance of releasing oxygen, generally in the excited singlet state, under heating or ultra violet (UV) irradiation. [4] Functional materials constructed with polycyclic aromatic compounds or EPOs can conduct the binding of oxygen upon light irradiation or with thermal treatment. [5] Therefore,t he reversible chemical binding of oxygen has significant advantages,such as better stability and more controllability,c ompared with physical adsorption. [6] However,t hese materials suffer from structural amorphism and poor solubility,w hich limit both practical applications and fundamental studies on their structural optimization for the precise control of O 2 capture and release.Metal-organic frameworks (MOFs) are porous crystalline materials and used extensively for aw ide range of applications from basic research to practical utilizations,i ncluding adsorption and separation of guest molecules,p roviding active catalytic sites and fabrication of drug delivery systems. [7] Theh ybrid nature of MOF offers an almost infinite suite of building blocks that can be manipulated to construct functional MOF through introducing open metal coordinate sites and functional groups into the framework. [8] Generally, the chemical transformation of building blocks in MOF involves irreversible or passive interaction, which may lead to the damage of crystalline structure. [9] It is difficult to control the spatial configuration transformation of linkers and the structure stability of MOF,t hus,t he chemistry occurring at the interface between the framework and an incoming substrate. [10] To our best knowledge,t he reversible binding of guest molecule triggered by th...

Absorbable sutures have moved to the forefront in surgical fields with a huge market. Antibacterial activity is one indispensable feature of the next generation of absorbable sutures. This study develops...

An immune system is of vital importance for maintaining the host health. Taking advantage of innate merits of immune cells, cell‐based immunotherapy has demonstrated great potentials for treating many severe diseases, especially for cancers and inflammatory diseases. However, the success of this promising therapy modality suffers from complex and immunosuppressive conditions generated along with disease development. The combination among cellular biology, nanotechnology, and material science offers vast opportunities to improve therapeutic efficacy and expand function. This review introduces recent advance in exploiting nanotechnology and materials to initiate and reinforce therapeutic functions of live immune cells, including monocyte, macrophage, dendritic cell, and T lymphocytes. The major strategies in artificially engineered cell immunotherapy are briefly summarized, and the possible developing trend in this field is discussed.

Live cells are implicated in diverse biological processes, including nutrient transport and removal of foreign substances. Their intelligent biofunctions with complex mechanisms cannot be replicated at all in man‐made materials despite the significant advance in material design. Taking advantages of their biocompatibility and biotropic capability, various live cells have been developed as a kind of special carriers for the on‐demand delivery of therapeutic and diagnostic agents in recent years. Furthermore, synthetic materials can be integrated with live cells to provide bio‐hybrid systems that inherit advantages from both the synthetic particles and the natural cells. Herein, recent strategies and advances in cell‐based bio‐hybrid delivery systems for disease treatment are summarized. Challenges and opportunities in this field are also discussed.

Polycyclic aromatic derivatives can trap 1 O 2 to form endoperoxides (EPOs) for O 2 storage and as sources of reactive oxygen species.H owever,t hese materials suffer from structural amorphism, which limit both practical applications and fundamental studies on their structural optimization for O 2 capture and release.Metal-organic frameworks (MOFs) offer advantages in O 2 binding,such as clear structure-performance relationships and precise controllability.Herein, we report the reversible binding of O 2 is realized via the chemical transformation between anthracene-based and the corresponding EPO-based MOF.Itisshown that anthracene-based MOF,the framework featuring linkers with polycyclic aromatic structure,c an rapidly trap 1 O 2 to form EPOs and can be restored upon UV irradiation or heating to release O 2 .Furthermore,we confirm that photosensitizer-incorporated anthracene-based MOF are promising candidates for reversible O 2 carriers controlled by switching Vis/UV irradiation.Endoperoxides (EPOs) have interesting photochemical and thermodynamic properties. [1] Their potential applications for reversible oxygen storage and as chemical sources of reactive oxygen species,h ave made these compounds the focus of many fundamental investigations. [2] Many polycyclic aromatic derivatives could trap the singlet oxygen ( 1 O 2 )t of orm EPOs. [3] EPOs exhibit the exceptional performance of releasing oxygen, generally in the excited singlet state, under heating or ultra violet (UV) irradiation. [4] Functional materials constructed with polycyclic aromatic compounds or EPOs can conduct the binding of oxygen upon light irradiation or with thermal treatment. [5] Therefore,t he reversible chemical binding of oxygen has significant advantages,such as better stability and more controllability,c ompared with physical adsorption. [6] However,t hese materials suffer from structural amorphism and poor solubility,w hich limit both practical applications and fundamental studies on their structural optimization for the precise control of O 2 capture and release.Metal-organic frameworks (MOFs) are porous crystalline materials and used extensively for aw ide range of applications from basic research to practical utilizations,i ncluding adsorption and separation of guest molecules,p roviding active catalytic sites and fabrication of drug delivery systems. [7] Theh ybrid nature of MOF offers an almost infinite suite of building blocks that can be manipulated to construct functional MOF through introducing open metal coordinate sites and functional groups into the framework. [8] Generally, the chemical transformation of building blocks in MOF involves irreversible or passive interaction, which may lead to the damage of crystalline structure. [9] It is difficult to control the spatial configuration transformation of linkers and the structure stability of MOF,t hus,t he chemistry occurring at the interface between the framework and an incoming substrate. [10] To our best knowledge,t he reversible binding of guest molecule triggered by th...