Pediatric patients with Crohn's disease with both nonfistulizing and fistulizing disease have worse clinical outcomes. Nonfistulizing disease is a risk factor for the development of fistulizing disease over time.
Different treatment protocols for bronchiolitis were used in three paediatric wards in this real-life study. No treatment regimen proved superior. Inhalations of hypertonic saline or adrenaline were associated with a longer hospital stay.
Background
Protracted febrile myalgia syndrome (PFMS) is a rare complication of Familial Mediterranean fever (FMF). The diagnosis is based on clinical symptoms and is often challenging, especially when PFMS is the initial manifestation of FMF. The aim of this report was to describe the magnetic resonance imaging (MRI) findings in pediatric patients with PFMS.
Results
There were three girls and two boys ranging in age from 6 months to 16 years, all of Mediterranean ancestry. Three had high-grade fever, and all had elevated inflammatory markers. MRI of the extremities yielded findings suggestive of myositis, which together with the clinical picture, normal CPK levels, and supporting family history of FMF, suggested the diagnosis of PFMS. Out of most common MEFV mutations tested, one patient was homozygous for M694V mutation, three were heterozygous for M694V mutation, and one was compound heterozygous for the M694V and V726A mutations.
Conclusions
MRI may serve as an auxiliary diagnostic tool in PFMS.
Aim To evaluate the effectiveness of various treatment regimens for bronchiolitis in hospitalised children in three general paediatric wards in which different treatment protocols are customary. Patients and methods Data was retrospectively collected for all hospitalised children under two years of age with clinical bronchiolitis, between October 2012 and March 2013. Results During the study, a total of two hundred eighty six children were hospitalised with bronchiolitis in wards A, B and C. Clinical and laboratory parameters upon admission were similar among the patients in the three wards. The treatment differed between the wards, as in ward C, use of antibiotics and hypertonic saline inhalations was significantly less (p < 0.001). Admission course and outcome were also significantly different among the wards: mean number of days with measured saturation < 92% and mean length of hospital stay were lower in ward C compared to wards A and B (1.8 days vs. 2.8 and 2.9 days, p = 0.001 and 3.9 days vs. 5.0 and 4.4, p = 0.012, respectively).Multivariate analysis showed that low saturation upon admission, higher WBC count and the use of hypertonic saline inhalations were predictive of a longer period of saturation < 92% and a longer hospital stay. Similar results were found in the subgroup of two hundred and three children with positive respiratory-syncytial-virus nasal wash. Conclusions No proof was found as to the added effectiveness of different treatments in bronchiolitis. Furthermore, the use of hypertonic saline inhalations might be associated with a longer period of low saturation and a longer hospital stay. Introduction Croup is one of the most common respiratory illnesses presenting to the emergency department (ED) in early childhood. The epidemiology of this disease was analysed. Methods During the 14 years period from 1995 to 2008 a total number of 4914 children aged 0-14 years, who made crouprelated visits to EDs in the city of Vinnytsya, Ukraine, were identified to obtain all encounters for croup made by children. Results During the study period, the annual incidence of croup had varied from 45.7 to 96.6 cases per 10 000 child population (Figure). Since 2005, annual incidence rates had increased. Most children (85.7%) were younger than 6 years of age; the peak incidence occurred during the second year of life (24.4%); the male to female ratio was 2.2:1.69.1% of children had 1 croup episode, 21.5% -2-3 croup episodes, 9.4% -4 or more croup episodes.
PO-0207 EPIDEMIOLOGY OF STENOSING LARYNGOTRACHEITIS (CROUP) IN CHILDREN IN THE CITY OF VINNYTSYA, UKRAINEConclusions Croup is one of the respiratory illnesses in early childhood. The boys are more commonly affected than girls. The risk of croup recurrence is high. Introduction Seasonal variation in croup has been well documented by at least 12 reports, bat there are some regional differences. Evidence is lacking, however, for daily variation in croup. Aims To determine seasonal and daily variation in croup. Methods We reviewed all emergency department calls for...
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