The treatment of malignant tumors following surgery is important in preventing relapse. Among all the post-surgery treatments, immunomodulators have demonstrated satisfactory effects on preventing recurrence according to recent studies. Ginsenoside is a compound isolated from panax ginseng, which is a famous traditional Chinese medicine. Ginsenoside aids in killing tumor cells through numerous processes, including the antitumor processes of ginsenoside Rh2 and Rg1, and also affects the inflammatory processes of the immune system. However, the role that ginsenoside serves in antitumor immunological activity remains to be elucidated. Therefore, the present study aimed to analyze the effect of ginsenoside Rh2 on the antitumor immunological response. With a melanoma mice model, ginsenoside Rh2 was demonstrated to inhibit tumor growth and improved the survival time of the mice. Ginsenoside Rh2 enhanced T-lymphocyte infiltration in the tumor and triggered cytotoxicity in spleen lymphocytes. In addition, the immunological response triggered by ginsenoside Rh2 could be transferred to other mice. In conclusion, the present study provides evidence that ginsenoside Rh2 treatment enhanced the antitumor immunological response, which may be a potential therapy for melanoma.
Because of advantages such as remarkable mechanical properties and the ease of recycling, fiber‐reinforced thermoplastic polymer composites have been increasing in importance in industrial, transport, and sporting potential extraordinary applications. To fabricate polycarbonate (PC) components with lightweight and high mechanical properties, short glass fiber (SGF), long carbon fiber (LCF) reinforcement, and foaming technology were used in this study. The effects of SGF, LCF, and SGF/LCF on the mechanical properties and foaming quality of PC samples were carefully investigated and compared. The results show that SGF has a better foaming nucleation effect than LCF, and the mechanical enhancement effect of LCF is more significant than that of SGF. The combination of SGF and LCF can effectively improve the cell quality of foam samples and significantly enhance their mechanical properties. Therefore, a comprehensive application of the fiber‐reinforcement effect of PC resin is proposed.Highlights LCF and SGF reinforced PC foams have been successfully fabricated. Hybrid reinforced effect of LCF and SGF on PC foams was verified.
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