We developed a facile
method for fabricating large-area, two-dimensional (2D), organic,
highly crystalline films and extended it to organic thin-film transistor
arrays. Tilted spinning provided oriented flow at the three-phase
contact line, and a 2D crystalline film that consisted of layer-by-layer
stacked 2,7-diocty[1]benzothieno[3,2-b]benzothiophene
(C8-BTBT) was obtained facilely for organic thin-film transistors
(OTFTs). The extracted field-effect mobility is 4.6 cm2 V–1 s–1, but with nonideal features.
By applying this method to microdroplet arrays, an oriented crystal
was fabricated, and the channel region for OTFTs was covered by adjusting
the spinning speed. By tuning the tilt angle (θ) of the revolving
substrate, we fabricated high-performance OTFT arrays with average
and maximum mobilities of 7.5 and 10.1 cm2 V–1 s–1, respectively, which exhibited high reliability
factors of over 90% and were close to that of ideal transistors. These
results suggest that high-quality crystalline films can be obtained
via a facile tilted-spinning method.
An easily accessible method is proposed for the fabrication of a 3D micro/nano dual-scale carbon array with a large surface area. The process mainly consists of three critical steps. Firstly, a hemispherical photoresist micro-array was obtained by the cost-effective nanoimprint lithography process. Then the micro-array was transformed into hierarchical structures with longitudinal nanowires on the microstructure surface by oxygen plasma etching. Finally, the micro/nano dual-scale carbon array was fabricated by carbonizing these hierarchical photoresist structures. It has also been demonstrated that the micro/nano dual-scale carbon array can be used as the microelectrodes for supercapacitors by the electrodeposition of a manganese dioxide (MnO2) film onto the hierarchical carbon structures with greatly enhanced electrochemical performance. The specific gravimetric capacitance of the deposited micro/nano dual-scale microelectrodes is estimated to be 337 F g−1 at the scan rate of 5 mV s−1. This proposed approach of fabricating a micro/nano dual-scale carbon array provides a facile way in large-scale microstructures’ manufacturing for a wide variety of applications, including sensors and on-chip energy storage devices.
Depression is a global health problem with growing prevalence rates and serious impacts on the daily life of patients. However, the side effects of currently used antidepressants greatly reduce the compliance of patients. Quercetin is a flavonol present in fruits, vegetables, and Traditional Chinese medicine (TCM) that has been proved to have various pharmacological effects such as anti-depressant, anti-cancer, antibacterial, antioxidant, anti-inflammatory, and neuroprotective. This review summarizes the evidence for the pharmacological application of quercetin to treat depression. We clarified the mechanisms of quercetin regulating the levels of neurotransmitters, promoting the regeneration of hippocampal neurons, improving hypothalamic-pituitary-adrenal (HPA) axis dysfunction, and reducing inflammatory states and anti-oxidative stress. We also summarized the antidepressant effects of some quercetin glycoside derivatives to provide a reference for further research and clinical application.
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