A spectrum of diverse prevention methods that offer high protection against HIV has posed the following challenge: how can national AIDS policies with high coverage for prevention and treatment make the best use of new methods so as to reverse the current high, and even rising, incidence rates among specific social groups? We conducted a narrative review of the literature to examine the prevention methods and the structural interventions that can have a higher impact on incidence rates in the context of socially and geographically concentrated epidemics. Evidence on the protective effect of the methods against sexual exposure to HIV, as well as their limits and potential, is discussed. The availability and effectiveness of prevention methods have been hindered by structural and psychosocial barriers such as obstacles to adherence, inconsistent use over time, or only when individuals perceive themselves at higher risk. The most affected individuals and social groups have presented limited or absence of use of methods as this is moderated by values, prevention needs, and life circumstances. As a result, a substantial impact on the epidemic cannot be achieved by one method alone. Programs based on the complementarity of methods, the psychosocial aspects affecting their use and the mitigation of structural barriers may have the highest impact on incidence rates, especially if participation and community mobilization are part of their planning and implementation.

BackgroundPoint-of-care (POC) screening for HIV and syphilis using rapid testing was implemented in indigenous communities in the triple-border area of the Brazilian Amazon. We describe the context of the early introduction of POC screening, explore hindering and enabling factors for POC implementation, and recommend strategies for feasible, viable, and sustainable syphilis and HIV screening interventions.MethodsThis was a qualitative study based on grounded theory methodology. Data were collected using in-depth interviews, semi-structured questionnaires, and field observations and were analysed using the framework approach. Qualitative information was complemented by quantitative data for descriptive purposes.ResultsAn overall high score for vulnerability to acquiring HIV and syphilis was observed among the indigenous communities. Health professionals reported satisfactory rapid testing acceptance, although concerns were raised about the pain of the fingerprick. Counselling-related challenges included ensuring the accuracy of translations, collaborating with translators and communicating positive test results. Over 3 months, 86.7 % of the syphilis-positive individuals began treatment, and all of them notified their partners. Accessibility, measured as travel time via the local transportation network, was a barrier to health care access. A lack of gasoline for boats and other transportation was also a hindering factor at all levels of implementation.ConclusionsThe recommendations address the preparation phase at the coordination level as well as at the training level. Tools such as strengths, weaknesses, opportunities, and threats (SWOT) analyses; checklists; context-adapted protocols; and fact sheets are very simple methods to facilitate implementation. The findings of this study are important because they may inform the implementation of new health technologies in low-resource national disease control programmes in remote communities.

Background Brazil has considerably reduced the number of cases of malaria in recent years and aims to eradicate the disease completely, however, vivax malaria continues to be a major challenge for the health system. In this context, the key to building a successful elimination programme may lie in the knowledge and the perceptions of the health agents, the patients affected by the disease and the personnel responsible for malaria diagnosis, treatment and control at the local level. Methods A qualitative study was undertaken in Manaus, capital of the state of Amazonas, Western Brazilian Amazon, using a sample of 33 patients who were being treated for malaria and 22 health agents who were working in malaria diagnosis, treatment and control at the local level. A semi-structured interview with a further thematic analysis was performed. Results There are still many myths regarding malaria transmission and treatment that may hinder the sensitization of the population of this region in relation to the use of current control tools and elimination strategies, such as mass drug administration (MDA). Most health professionals reported that the abandonment of treatment for malaria by the patient is related to poor social conditions, the high incidence of alcoholism and the low level of schooling of the affected population. One negative perception, observed in both groups with regard to the use of insecticide-treated nets, is that they may cause skin irritations and allergies. Most patients and health professionals have described malaria as an impossible disease to eliminate because it is intrinsically associated with forest landscapes, and according to them, elimination would only be possible if there were a vaccine against malaria. Conclusion In the Amazon, cultural perceptions about the etiology of this disease can influence the behaviour and practices that social groups adopt in relation to the different forms of living in a malaria-endemic context. Negative perceptions about malaria elimination can act as a barrier when trying to reach proper coverage for control strategies such as mosquito nets and MDA. Electronic supplementary material The online version of this article (10.1186/s12936-019-2854-3) contains supplementary material, which is available to authorized users.

Anthropological study carried out by ethnographic method within the members of two HIV support groups for people living with HIV/AIDS, in the city of Brasilia. The research aims to understand the potential benefits of these forms of social organization for facing the daily life with the virus and the contribution to antiretroviral adherence. The methodological approach focused on the development of ethnographic work which included techniques such as participant observation and interviews with members and group coaches. Results led to the identification of interacting mechanisms within health staff and people living with HIV/AIDS, the adoption of attitudes to deal with the drug prescription, and input provided by the group to improve adherence to ARV by highlighting the role of networking and peer support. Keywords: Adherence; Aids; Ethnography; Support Groups. Isabelle Picelli

Objetivo. Mostrar las narrativas de miembros brasileños de los equipos de salud de la familia acerca del humanismo percibido en la práctica de los cooperantes cubanos del programa Mais Médicos. Métodos. Estudio de caso descriptivo de corte transversal. Se aplicó una entrevista semiestructurada a miembros brasileños de los equipos de salud de la familia que trabajaran desde el inicio del programa con médicos cubanos en municipios seleccionados inscritos en el programa Mais Médicos, con 20% o más de su población en extrema pobreza, y menos de cinco médicos o una tasa de 0,5 médicos por 1 000 habitantes antes del programa. Se procesaron los datos mediante la técnica de análisis de contenido. Resultados. Se entrevistaron 30 licenciados y 28 técnicos en enfermería, 1 técnico administrativo y 19 agentes sanitarios. Los entrevistados valoraron positivamente el trabajo de los médicos cooperantes cubanos y resaltaron su responsabilidad, ética y humanismo, así como la elevada calidad de las consultas médicas y sus buenas relaciones con los pares de la atención básica. Conclusiones. Se constataron diferencias en los patrones de atención de los médicos cooperantes cubanos del programa Mais Médicos con respecto a los médicos que ejercieron en las comunidades estudiadas antes de la implantación de ese programa. Entre los rasgos diferenciales de los médicos cubanos resaltados más frecuentemente figuran el compromiso con la población —tanto en la consulta médica como en la solución de sus problemas—, la empatía, el respeto y, en general, el humanismo con el que tratan a los pacientes.

Umbilical cord blood banks have been created worldwide after the discovery that umbilical cord blood (UCB) is a rich source of Hematopoietic Stem Cells (HSC) and an alternative to HSC from bone marrow for allogeneic transplantation. According to Brazilian legislation, banks for allogeneic use (government services) and exclusively autologous use (private services) can be created in the country. The storage of UCB units for direct donation (family use) can occur in public cord blood banks, hemotherapy services and transplant centers when there is a specific need to treat a known patient that is a member of the newborn's family. Even with the legislation being quite clear about the creation of cord blood banks and distribution of UCB units, ANVISA has identified an interest, demonstrated by the population and regulated sector, in the possibility of releasing UCB units, stored in autologous cord blood banks, with the purpose of clinical applicability to another family member other than the newborn owner of the cells. The objective of this study is to promote a discussion on a possible alteration in the legal parameters that support the implementation of autologous cord blood banks, towards the constitution of private banks for family use, pointing out the main issues. The study analyzed the technical and legal criteria related to cord blood banks, described the characteristics of HSC from different sources and types of transplant donations and procedures; discussed concerns related to Bioethical principles, current and potential clinical HSC applications, and possibly risks and benefits. Rev. Bras.