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The Born cross section for the process e þ e − → pp is measured using the initial state radiation technique with an undetected photon. This analysis is based on datasets corresponding to an integrated luminosity of 7.5 fb −1 , collected with the BESIII detector at the BEPCII collider at center of mass energies between 3.773 and 4.600 GeV. The Born cross section for the process e þ e − → pp and the proton effective form factor are determined in the pp invariant mass range between 2.0 and 3.8 GeV=c 2 divided into 30 intervals. The proton form factor ratio (jG E j=jG M j) is measured in 3 intervals of the pp invariant mass between 2.0 and 3.0 GeV=c 2 .