Background Birdshot retinochoroiditis (BRC) is a rare and chronic bilateral uveitis mostly found in Caucasians. As few data are available about the clinical course of BRC in Hispanic patients, we aimed to report the clinical findings and the evolution of BRC in Brazilian patients. Methods This retrospective cohort multicenter nationwide study was performed by analyzing the records of patients with BRC diagnoses from Brazilian ophthalmological centers from April 1995 to May 2020. Results Forty patients (80 eyes) with a diagnosis of BRC were evaluated. The mean age was 53 years, and there was no sex predominance. All tested patients (34/40) were positive for HLA-A29. The diagnosis of BRC was made following the Levinson et al. criteria, and all ancillary tests were performed to exclude differential diagnoses. Clinical signs and symptoms, such as complications and treatment, were described. Conclusions BRC evolution in Brazilian patients seems to have some peculiarities that diverge from the published literature available about Caucasians, as AS inflammation is higher in this population.

Minimally invasive glaucoma surgeries are surgical treatment alternatives for glaucoma aimed at reducing intraocular pressure with a better safety profile compared to traditional trabeculectomy. However, in spite of less invasive techniques, complications may develop in any surgical procedure. To the best of our knowledge, this is the first case report of anterior uveitis following combined treatment with cataract surgery and iStent inject® which addresses the management of postoperative inflammation. RESUMOAs cirurgias minimamente invasivas para glaucoma consistem em uma opção de tratamento cirúrgico para glaucoma, a qual promove redução da pressão intraocular com melhor perfil de segurança do que a trabeculectomia. Todavia, complicações são inerentes à realização de procedimentos cirúrgicos, apesar do uso de técnicas menos invasivas. Este é o primeiro relato que apresenta um caso de uveíte anterior após cirurgia combinada de catarata e iStent inject®, além de orientações quanto ao manejo do quadro inflamatório.

Introduction: Acute retinal necrosis is a rare form of infectious necrotizing retinitis that affects individuals regardless of sex or age. It is characterized by an acute panuveitis, with associated retinal periarteritis, progressing to a diffuse necrotizing retinitis and, eventually, to retinal detachment. This study aims to report a case of acute retinal necrosis, with unilateral involvement and presumed etiology by herpesvirus. Case description: A 67-year-old man, complaining of eye pain and low visual acuity in his right eye, with 15 days of evolution. He had reduced visual acuity, anterior and posterior uveitis, with lesions suggestive of acute retinal necrosis. The patient was tested for HIV, tuberculosis, syphilis, toxoplasmosis and herpesvirus. He presented positive IgM and IgG for cytomegalovirus and positive IgG for herpes simplex virus, only. Despite the positive IgM for CMV, the treatment with Acyclovir was sustained due to the strong etiological suspicion of herpes simplex. The patient evolved with good response to treatment, progressing with clinical and visual improvement. Discussion: Acute retinal necrosis cases due to infection are frequently related to herpes simplex and varicella zoster viruses, but other viruses of the same family should be investigated. The diagnosis is clinical, in most cases, but etiological confirmation can be performed. The analysis of clinical and epidemiological factors, associated with the according classification of the onset uveitis and the observation of ophthalmological findings is a solid based thread for the etiological definition and for better management of the case. Complementary exams must be carefully requested, and the results must be associated with the clinical presentation before the medical conduct is chosen.