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Abstract:Chengde chromium-bearing vanadium-titanium magnetite (CCVTM) has been used as an important mineral resource in sinter making. The MgO content of this sinter can be enhanced by adding dolomite, which improved operation of the blast furnace. The effects of MgO in the form of dolomite on metallurgical properties, microstructure and mineral compositions of CCVTM sinter were studied by a sinter pot test, X-Ray Diffraction (XRD), Scanning Electron Microscope (SEM), and mineral phase microanalysis. The results were as follows: The flame front speed and sinter coefficient decreased with an increase in MgO content from 2.66 to 3.86% by adding dolomite. With an increase in MgO content from 2.66 to 3.86%, the flame front speed, sintering utilization factor, and the value of RI decreased, while RDI and the softening-melting properties improved. In addition, the value of sinter strength (TI) reached a maximum value at MgO = 3.56%. In addition, an increase in the abundance of magnetite, magnesium ferrite, and silicate phase, as well as a decrease in hematite, was found with an increase in MgO content. We concluded that the most appropriate MgO content in the sinter is 3.56%.

BACKGROUND: Acute organophosphorus pesticide poisoning (AOPP) is becoming a significant problem and a potential cause of human mortality because of the abuse of organophosphate compounds. This study aims to determine the independent prognostic factors of AOPP by using multivariate logistic regression analysis. METHODS: The clinical data for 71 subjects with AOPP admitted to our hospital were retrospectively analyzed. This information included the Acute Physiology and Chronic Health Evaluation II (APACHE II) scores, 6-h post-admission blood lactate levels, post-admission 6-h lactate clearance rates, admission blood cholinesterase levels, 6-h postadmission blood cholinesterase levels, cholinesterase activity, blood pH, and other factors. Univariate analysis and multivariate logistic regression analyses were conducted to identify all prognostic factors and independent prognostic factors, respectively. A receiver operating characteristic curve was plotted to analyze the testing power of independent prognostic factors. RESULTS: Twelve of 71 subjects died. Admission blood lactate levels, 6-h post-admission blood lactate levels, postadmission 6-h lactate clearance rates, blood pH, and APACHE II scores were identified as prognostic factors for AOPP according to the univariate analysis, whereas only 6-h post-admission blood lactate levels, post-admission 6-h lactate clearance rates, and blood pH were independent prognostic factors identified by multivariate logistic regression analysis. The receiver operating characteristic analysis suggested that post-admission 6-h lactate clearance rates were of moderate diagnostic value. CONCLUSIONS: High 6-h post-admission blood lactate levels, low blood pH, and low post-admission 6-h lactate clearance rates were independent prognostic factors identified by multivariate logistic regression analysis. Key words: acute organophosphorus pesticide poisoning (AOPP); multivariate logistic regression analysis; independent prognostic factors; receiver operating characteristic curve. [Respir Care 2016;61(7):965-970.

High-chromium vanadium and titanium magnetite (HCVTM) sinter has poor properties. The coke ratio has an important effect on the behavior of HCVTM sintering as it affects the mineral phases in the high-chromium vanadium and titanium sinter (HCVTS) via changing the sintering temperature and atmosphere. In this work, the sintering behavior of HCVTM mixed with varying coke ratios was investigated through sintering pot tests, X-ray diffraction (XRD), gas chromatographic analysis, and mineral phase analysis. The results show that, with the increase of the coke ratio from 4.0% to 6.0%, leading to the increase of the combustion ratio of the flue gas, the vertical sintering rate and sinter productivity decrease. Meanwhile, with the change of the coke ratio, the content of magnetite, silicate, and perovskite increase, while the hematite and calcium ferrite decrease. In addition, the tumble strength and reduction ability of HCVTS decrease, and its degradation strength increase. It was found that the appropriate coke ratio for the sintering process was 5.0 wt %.

This study aimed to investigate the effect of norisopoldine (NOR) on acute lung injury in septic mice. Lipopolysaccharide (LPS) was used to establish sepsis induced acute lung injury (ALI) in mice. The dry and wet weight of mice lung was detected, and the pathological changes of lung were observed by hematoxylin and eosin (H&E) staining. Bronchoalveolar lavage fluid (BALF) was detected. Inflammatory factors in BALF were detected by enzyme-linked immunosorbent assay (ELISA). The polarization of macrophages in lung tissue was detected by flow cytometry. The markers of M1 and M2 macrophages were detected by RT-PCR. LPS induced RAW264.7 cells were treated with NOR. Inflammatory response, macrophage polarization, glycolysis, and M2 pyruvate kinase (PKM2)/hypoxia inducible factor-1α (HIF-1α)/peroxisome proliferator activated receptor-γ co-activator 1-α (PGC-1α) signaling pathway were detected. NOR could effectively alleviate sepsis induced ALI, and reduce the number of total cells, total protein concentration, neutrophils, macrophages in BALF. NOR decreased the level of inflammatory factors and promoted macrophages from M1 to M2 type in vivo and vitro. Moreover, NOR could activated PKM2, and inhibited PKM2 from cytoplasm to nuclear, attenuated HIF-1α expression, and increased PGC-1α and peroxisome proliferator-activated receptor (PPAR)-γ expression. In addition, NOR inhibited glycolysis and promoted oxidative phosphorylation in RAW264.7 cells. Furthermore, PKM2 inhibitors could reverse the effect of NOR on PKM2/HIF-1α/PGC-1α signaling pathway in RAW264.7 cells. NOR alleviated sepsis induced AIL in mice, inhibited the inflammatory response, promote M2 polarization of macrophages through regulating PKM2/HIF-1α/PGC-1α signaling pathway.