Изучены изменения лейкоцитарных индексов крыс с адъювант-индуцированным ревматоидным артритом при лечении в течение трех недель препаратами базисной терапии и инновационными экспериментальными средствами. Не выявили отличий между эффектами от лечения базисными препаратами и экспериментальными препаратами на основе антисмысловых олигонуклеотидов, что свидетельствует об их схожей эффективности. Ключевые слова: гематологические показатели, ревматоидный артрит, антисмысловые олигонуклеотиды, фактор некроза опухоли Changes in leukocyte indices of rats with adjuvant-induced rheumatoid arthritis were studied after three weeks of treatment with basic therapy drugs and innovative experimental means. No differences were found between the effects of treatment with basic drugs and experimental drugs based on antisense oligonucleotides, which indicates their similar effectiveness.
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