PICO question
Is there a decrease of caseous lymphadenitis in vaccinated sheep compared to unvaccinated sheep?
Clinical bottom line
The evidence provided by the studies used is strong (all have been randomised controlled trials), supporting the hypothesis that sheep vaccinated against caseous lymphadenitis (CLA) are less likely to develop the disease when compared to unvaccinated sheep. Vaccination may be a useful tool in the prevention and control of clinical CLA following a risk assessment.
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