In the present study was undertaken to evaluate the mucilage obtained from the calyx of flower of Hibiscus rosasinensis Linn as a suspending agent. A suspension of CaCO3 was prepared using 2 % w/v of hibiscus mucilage as suspending agent and it is evaluated for its stability using the parameters like, sedimentation volume, viscosity, redispersibility and pH. The suspending effect of hibiscus mucilage was compared with CaCO3 suspensions prepared using 2 % w/v of suspending agents such as acacia and tragacanth. The results obtained indicated that the hibiscus mucilage could be used as a suspending agent. It has low rate of sedimentation, high viscosity, slightly basic pH and is easily redispersible. These effects were comparable with that of the standard suspending agents like acacia and tragacanth. The mucilage isolated from the calyx of flower of Hibiscus rosasinensis can be used as a pharmaceutical adjuvant.
Cancer cause sickness and consequently can be viably overwhelmed by a multi-constituently remedial strategy. Herbal extracts shows the example of such stratagem. However, less research have been carried out till date that portray the effect of different extraction techniques on the phyto compounds profile of plant extracts and its effect on anticancer activity. Momordica charantia is a member of the Cucurbitaceae. It is a popular vegetable harvest in Indian customary medicine since olden times. It has potential lipid lowering and antioxidant activity and antidiabetic. In the present study, we have evaluated the anticancer prospective of methanolic and acetone extracts of Momordica charantia (MCME) and (MCAE). Reported results show that (MCME) is rich in bioactive compounds shown anticancer activity with Cell lines of (IC50) with MCF 715.6 ± 1.3 and HeLa 28.2 ± 1. This study based on the presence of cytotoxic from the Momordica charantia, which have been further used in herbal formulations study as an anticancer activity. Our conclusion support additional indepth study of this pharmacologic activity as a malignant tumour agent.
Medical professionals and patients alike are aware of the advantages of using medicinal plants, which have been utilised for centuries. Due to their superior therapeutic qualities because they are less likely to have side effects than current medications, the herbal treatment contributes to an improvement in therapeutic value. Nanostructured formulations are used to make herbal medicines more soluble and to help localize the medicine in a particular place, improving its efficacy and safety. Polymeric nanoparticles are colloidal structures that function as drug release control and localization vectors. They can be used to reduce the toxicity and side effects of pharmaceuticals while also increasing bioavailability. In this paper, we will discuss the advantages and disadvantages of nanostructured drug delivery systems.
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