Overdenture (OD) is applied in removable prosthodontics also for the prevention of the reduction of edentulous alveolar ridge. The features of various restorative materials are to be respected in planning for the filling of cavities of abutment teeth. Concerning longevity of restoration, glass ionomer cements are promised to be the most acceptable choice due to its fluoride dynamics and resistance to wet condition. Implant retained OD by additional remained restored teeth are good combination according to the literature data. Frequent controls in terms of six months are wishful because of posibility of secondary caries and periodontal pathology when preventive measurements (fluoridation, scaling) might be processed.

Aim. To identify potential risk factors for the development of subclinical hypothyroidism following long‐term valproic acid monotherapy in children with epilepsy. Methods. Serum levels of thyroid‐stimulating hormone, free thyroxine, free triiodothyronine, thyreoglobulin antibodies, and thyroid peroxidase antibodies were determined in 41 patients and in 41 sex‐ and age‐matched healthy children. Results. Mean valproic acid treatment duration was 2.80±1.96 years. The valproic acid group had higher serum thyroid‐stimulating hormone (p<0.001) and free triiodothyronine (p<0.05) levels compared to the control group. Serum thyroid‐stimulating hormone and free triiodothyronine were above the upper limit for healthy controls in 34% and 32% of patients, respectively, and no clinical features of thyroid dysfunction were observed. Duration of valproic acid monotherapy for less than four years was a risk factor for elevated thyroid‐stimulating hormone levels. Conclusion. One third of children with normal range serum valproic acid levels may have elevated serum thyroid‐stimulating hormone and free triiodothyronine levels, especially in the first four years of treatment.

Background and Aim: Adverse effects are common in children treated with antiepileptic medications and may affect parental beliefs about treatment. The aim of the study was to investigate the relationship between adverse effects and parental beliefs about antiepileptic drugs used for the treatment of their children. Methods: The study was performed at the University Children’s Hospital, Belgrade, Serbia from 2013–2015. Parents of children treated with valproic acid, carbamazepine or lamotrigine, were eligible. They were asked to fill in the Beliefs about Medications Questionnaire (BMQ) and The Liverpool Adverse Events Profile (LAEP). Results: Parents of 127 children (average age 9.88 ± 4.16 years) of whom 111 had epilepsy (67 generalized, 44 focal) and 16 with febrile seizures participated in the study. Nervousness and/or agitation, weight gain, restlessness, headache, difficulty in concentrating, feeling of aggression and upset stomach were most frequent adverse effects, reported in 37% of the population. BMQ-specific necessity scores significantly correlated with parental education; parents with elementary school showed lower scores than those with higher education. The presence of difficulty in concentrating of their child was associated with higher BMQ concern scores (20.73 ± 4.25 vs. 18.99 ± 3.60, p = 0.043) as well as necessity scores (18.42 ± 3.31 vs. 16.40 ± 2.73, p = 0.017). Higher scores of BMQ-general overuse were reported in the presence of a headache (8.79 ± 2.81 vs. 7.64 ± 2.72, p = 0.027). Conclusions: The main finding of our study is that parental beliefs about antiepileptic drugs were associated with the presence of adverse effects. Understanding this relationship could allow physicians and pharmacists to structure better educational programs for parents of children treated with antiepileptic drugs. Education should be more focused towards understanding the adverse effects of antiepileptics which could alleviate parental concerns and strengthen their beliefs about the necessity of medication use in their children.

ABSTRACT. The aim of the present study was to determine the porcine circovirus type 2 (PCV2) prevalence in boars in 3 farms in Serbia and their possible relation with alterations of reproductive parameters and blood biochemical parameters [total protein, urea, creatinine and aspartate transaminase levels (AST)]. The prevalence of (PCV2) was evaluated by the presence of specific antibodies. An ELISA assay was used for the detection of PCV2 antibodies in 58 boars' blood sera from Serbian commercial farms, among which 48 were from and reared in the Serbian farms, and 10 were imported from different European Union (EU) countries.Anti PCV2 IgM and/or IgG were detected in sera of 51 (87.93%) boars. Based on the type of antibodies (IgM and IgG PCV2 antibodies), it was concluded that chronic PCV2 infection was the predominant type in tested boars. The imported boars did not have an active infection titer. Biochemical tests in blood didn't show significant differences between PCV2 positive and negative boars. The recorded high prevalence of PCV2 antibodies among boars indirectly proved that PCV2 has been wide spread in the examined farms. Significant difference in the frequency of active, recent and chronic PCV2 infection in boars was found among three farms (p<0.05). Imported boars did not show significant difference in terms of active, recent or chronic PCV2 infection in comparison with boars deriving from Serbian farms http://epublishing.ekt.gr | e-Publisher: EKT | Downloaded at 11/05/2018 18:48:27 |

Introduction. The flow of endodontic sealer (ES) is the property that characterizes its velocity along the certain surface and depends on the friction force. The aim of this research was to measure the flow rate of three zinc oxide eugenol based ES?s in various consistencies exposed to the load of 2 kg. Material and methods. The experimental group included prepared samples of sealers protocoled by ADA specification No. 57 A) Endomethasone N in liquid:powder ratio of 1:5, 1:6, 1:7 (standard), 1:8 and 1:9 according to the manufacturer brochure depending on the clinical situation; B) Roth 801 as 1:7 (standard) and 1:8 mixtures C) Tubliseal EWT as standard preparation (base-catalyst 1:1). A volume of 0.05 ml sealer was spread on the glass plate and upon applying the load of 2 kg the diameter of sealer was measured. In the control group the sealer samples were loaded only by the weight of glass plate (0.1kg). Results. Based on measured diameters of sealers, all of them satisfied ADA requirements for the flow (d>20mm) (Endomethasone - 20.7-27.8 mm; Roth 801- 29.6-30.0 mm; Tubliseal -39.9 mm). The thin consistency of sealers (1:5, 1:6) showed significantly higher flow than standard mixture (1:7) (p < 0.05). Conclusion. Tubliseal EWT sealer showed the highest flow rate, significantly different than standard mixtures (1:7) of Endomethasone N and Roth 801.