There was no comparative difference seen in response to tahini in those children with eczema (n=26, t=0.296, p>0.05).There is statistically significant difference between exposure groups (eat sesame, never tried/empirical avoidance and previous reaction) in the difference between their tahini vs sesame wheal, (ANOVA (F(2,44)= 6.744, p=0.03)). The difference in reaction size between tahini and sesame was larger in those that have previously reacted (mean=2.00 ±2.45)) compared to those that never tried/empirically avoided sesame (mean=0.11±0.85)(p=0.02).Conclusions The results show greater reaction to tahini vs sesame, in the number of positive responses, and average size of response wheal. Importantly, the wheal size appears to be greater in those who have previously reacted compared to those who have avoided sesame.Those with eczema did not produce a greater mean difference between tahini and sesame wheal size, suggesting tahini is not acting as an irritant.Specific IgE and/or challenge testing could validate whether the additional positives (9/50) reflect true sesame allergy.
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