Background: The diseases of the musculoskeletal system are a serious problem among patients of older age groups, as they can lead to disability, dependence in everyday life and reduce the quality of life. Therefore, it is important to conduct geriatric evaluation in patients with gonarthrosis. The aim of the study: To study the peculiarities of the course of osteoarthrosis of knee joints in patients of senile age on the basis of complex geriatric evaluation. Materials and methods: We have studied clinical features of osteoarthritis of the knee joints in 249 patients of older age groups, including 123 patients of senior age and 126 elderly patients. Clinical features were studied with the help of a computer program to assess the geriatric status. The data was processed statistically. Results: We have shown that in people of senior age with osteoarthritis of the knee joints, in contrast to the elderly, there are more pronounced violations of stability and gait. In senior age, the risk of developing a syndrome of malnutrition is formed, cognitive abilities are reduced, lower indicators are characterized by a moral state, there is a significantly higher dependence on other people in daily activities, the quality of life is reduced. Conclusion: Osteoarthritis of knee joints in senior age is accompanied by systemic age-caused conditions, namely a more pronounced decrease in the quality of life as a whole by 24.5%. Age-related conditions in people over 75 can be identified through the use of a comprehensive geriatric assessment, which allows to timely identify a number of deviations and prescribe a set of therapeutic and preventive measures.
Objective: to develop a personalized rehabilitation program for improving age-related resilience (AR), antioxidant status (AOS), the quality of life and reducing pain in elderly patients with osteoarthritis (OA).Patients and methods. The program consisted of two parts. In the first part, we conducted a comparative study to assess the AR (Mahnach test), geriatric status, and AOS (amperometric flow-injection analysis) in 181 subjects in total, with coxarthrosis (n=92) and without it (n=89). The average age of patients in two groups was comparable: 72.1±1.1 and 71.9±1.1 years. Using factor analysis, we developed the personalized rehabilitation program based on the obtained data. The effectiveness of the program was evaluated in the second part of our work. We conducted an additional comparative study of changes in AR, AOS, severity of joint pain (by visual analogue scale, VAS) and quality of life (according to SF-36 questionnaire) in patients with coxarthrosis (n=114).Results and discussion. Patients with coxarthrosis had significantly lower level of AR, total antioxidant, and antiradical activity, and a higher content of Schiff bases as compared to subjects without coxarthrosis (p<0.05). The program of rehabilitation, which included a course of treatment with Chondroquard, significantly improved AR, AOS, quality of life and reduced hip pain compared to the standard OA therapy (p<0.05).Conclusion. The personalized rehabilitation program has a complex positive effect on pain, quality of life, AR and AOS in elderly patients with OA.
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