To evaluate the tear film and calculate the prevalence of dry eye in Rheumatoid Arthritis patients based on disease activity. Materials and Methods: A cross-sectional study of 50 Rheumatoid Arthritis patients was performed in the Department of Ophthalmology, Smt. Kashibai Navale Medical College and Hospital, Pune. C-Reactive Protein (CRP), and Rheumatoid Factor (RF) labs were done. All patients underwent complete ophthalmic evaluation including assessment of visual acuity. Tear film assessment was done by calculating the Tear Meniscus Height (TMH) on Anterior Segment-Optical Coherence Tomography (AS-OCT).Results: Fifty patients were studied. 44 were females and 6 were males with a mean age of 47.34 ± 10.33years. TMH was abnormal (≤300 microns) in 31 (62%) patients. RF was positive in 31 (62%) patients while CRP was raised (>3.0mg/L) in 30 (60%) patients. RF Positivity had a significant correlation with abnormal TMH values (χ 2 = 5.15, p=.02). Raised CRP was not significantly associated with abnormal TMH values (χ 2 = 0.39, p=.54).Conclusion: Dry eye evaluation should be considered in RA patients irrespective of the disease activity.
Purpose: To assess the inter-observer agreement and reliability of central topography (CT) of IOL Master 700 with that of Pentacam HR, as a screening tool for determining the suitability for premium (toric, monofocal and presbyopia correcting) intraocular lens (IOL) implants. Setting: Nethradhama Superspeciality Eye Hospital, Bangalore, India. Method: 200 eyes of eligible patients undergoing unilateral or bilateral phacoemulsification with premium IOL's were included in the study. Preoperatively, IOL Master 700 CT and Pentacam scans were performed for corneal topography evaluation. 2 experienced clinicians were randomised to interpret the axial map of either of the scans at a time and their responses were then enclosed in an envelope, and forwarded to a third observer for analysis. If there was a conflict, final decision was based on the interpretation of the Pentacam scan. Results: Of the total scans interpreted by the 2 observers, 77.5% (n = 155) showed agreement whereas 22.5% (n = 45) showed disagreement. The sensitivity, specificity, positive predictive value and negative predictive value (NPV) of IOL Master 700 CT in diagnosing irregular corneas when compared with Pentacam HR, was 72.73%, 78.09%, 29.09% and 95.86% respectively. The Cohen's κ inter-observer agreement value was 0.44, signifying a moderate degree of agreement, which was statistically significant (P < .00). Conclusions: High NPV of IOL Master CT suggested that the device efficiently ruled out irregular corneas, while any suspicious scan should be confirmed with Pentacam HR or a similar device for appropriate decision-making regarding premium IOL selection. Trial Registration Number: CTRI/2021/11/038053.
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