A new modified type of gating is presented that shows the ability to reduce the total scan time with almost conserved image quality compared with conventional gating. This new motion-adapted gating approach is based on a k-space-dependent gating threshold function. MR data acquired are only accepted if the motion-induced displacements measured from a reference position are below the chosen gating threshold function. During the MR measurement the scanner analyses respiratory motion decides in real-time which data in k-space could be measured according to the gating threshold function and performs data acquisition. In the present paper the approach will be described and discussed. Simulations based on in vivo data and initial in vivo experiments are presented to compare different variants of the new approach mutually and to the conventional technique. The analysis given is focused on spin warp type sequences, which are the best candidates for this approach.
Curved slice imaging based on multidimensional RF pulses is introduced and discussed. This new approach makes it possible to image curved anatomical structures by using MRI. The 2D RF or 3D RF pulses used can be tailored to excite or refocus transverse magnetization of a previously defined arbitrarily curved slice profile in a 3D space. These RF pulses can be integrated into all standard MRI sequences to perform slice selection. The final curved slice image is obtained as a projection of the curved slice magnetization onto a selected imaging plane. The problem of ambiguities arising due to this projection process is addressed. Phantom and in vivo experiments were performed to illustrate the advantages and limitations of this approach.
Fast proton magnetic resonance spectroscopic imaging (MRSI) using a multi-element head-coil array is examined with respect to three aspects: the coil design, the use of an appropriate signal combination method, and the design of the MRSI pulse sequence itself. An eight-element head-coil array has been developed to increase the signal-to-noise ratio (SNR) of MRSI in the human brain. The flexible wraparound design optimally fits different head sizes and thus provides high sensitivity. The signal combination of the individual coil elements is based on the approach proposed by Roemer et al. (Magn. Reson. Med. 16, 192 (1990)). An additional short prescan is performed to provide a good estimate of the complex coil sensitivity profiles, which are used in the signal combination procedure to correct the spectroscopic imaging data for the spatially varying intensity. The use of coil arrays in MRSI has some effect on the requirements for both water and lipid suppression. These techniques and a MRSI pulse sequence that provides a high spectroscopic resolution are described and discussed. Experimental results at 1.5 T show that metabolite maps of N-acetylaspartate (NAA), choline (Cho), phosphocreatine (PCr)/creatine (Cr) can be obtained within a 5-min acquisition time.
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