Background: Fetal cardiac rhabdomyoma is a rare condition. Case: We report a case with cardiac mass discovered in utero by prenatal ultrasonography at 33 weeks of gestational age. An echogenic round-oval shape mass at the interventricular septum protrudes to left ventricle was observed. Results: After birth, the baby was followed up for 7 months with echocardiography, physical examination, and computerized tomography scan, to rule out anything related to tuberous sclerosis. The prognosis depends on the size, site, number of tumors, and coexisting congenital abnormalities. Management highly depends on the presence of outflow tract obstruction of the heart. However, some cases may regress after birth.
Introduction: Preterm labor is one of the major problem and challenge in the obstetric field, since it is associated with high mortality and morbidity in newborn. Preterm delivery around 39.6% was thought to be caused by infection. One of the most common causes of preterm labor is Urinary Tract Infection (UTI). This study aims to determine the role of UTI in pregnancy as a risk factor for preterm labor.Method: This study is a case control study conducted from February 2019 to November 2019. This study involved 52 women (26 case group and 26 control group) with gestational ages over 20 weeks and under 37 weeks, where in case group with signs and symptoms of threatened of preterm delivery and in control group with no signs and symptoms of threatened of preterm delivery. The research sample is maternal peripheral blood for evaluation of Haemoglobin and mid stream urine for evaluation of Bacteriuria and Urine Culture - Resistance Test. Result: In this study, there were no differences in the value of characteristics of maternal age, gestasional age, and gravidity between the two groups (p> 0.05). Pregnancy with UTI (asymptomatic bacteriuria) increased the risk of preterm labor by 13 times compared to pregnancies without UTI (OR = 13.24; 95% CI = 1.53-114.30; p = 0.005 ).Conclusion: Based on the results of this study it can be concluded that a pregnancy with a UTI has a 13 times higher risk of experiencing preterm labor when compared to a pregnancy without a UTI.  Pendahuluan: Persalinan preterm adalah salah satu masalah dan tantangan dalam bidang obstetrik, terkait dengan tingginya mortalitas dan morbiditas pada bayi yang dilahirkan. Persalinan preterm sekitar 39,6% disebabkan oleh infeksi. Salah satu penyebab yang paling umum adalah Infeksi Saluran Kemih (ISK). Penelitian ini bertujuan untuk mengetahui peranan ISK dalam kehamilan sebagai faktor risiko terjadinya persalinan preterm.Metode: Penelitian ini adalah studi kasus kontrol yang dilakukan dari Februari 2019 hingga November 2019. Penelitian ini melibatkan 52 wanita (26 kelompok kasus dan 26 kelompok kontrol) dengan usia kehamilan lebih dari 20 minggu dan di bawah 37 minggu, di mana dalam kelompok kasus dengan adanya tanda dan gejala ancaman persalinan preterm dan dalam kelompok kontrol tanpa adanya tanda dan gejala ancaman persalinan preterm. Sampel penelitian adalah darah tepi ibu untuk keperluan menilai kadar Hemoglobin dan urin aliran tengah untuk keperluan evaluasi adanya Bakteriuria dan selanjutnya untuk Kultur Urin – Uji Resistensi.Hasil: Dalam penelitian ini, diketahui bahwa tidak ada perbedaan bermakna dalam karakteristik usia ibu, usia kehamilan, dan graviditas antara kedua kelompok (p>0,05). Diketahui bahwa kehamilan dengan ISK (bakteriuria asimptomatik) meningkatkan risiko persalinan preterm sebesar 13 kali dibandingkan dengan kehamilan tanpa ISK (OR = 13,24; IK 95%= 1,53-114,30; p = 0,005).Simpulan: Berdasarkan hasil penelitian ini disimpulkan bahwa kehamilan dengan ISK memiliki risiko 13 kali lebih tinggi mengalami persalinan preterm bila dibandingkan dengan kehamilan tanpa ISK.
Preterm delivery is the leading cause of death for children under 5 years of age worldwide. Preterm delivery is one of the significant factors causing neonatal death due to complications associated with preterm birth. Complications of preterm delivery account for about 16% of all deaths in children under 5 years, and 35% of total deaths of newborns. There are several broad outlines of factors associated with preterm labor, including stress, inflammation or infection, overdistention of the uterus and the hypothalamic-pituitary-adrenal axis. Several studies show the role of cortisol caused by these factors. This study aimed to assess the relationship of maternal serum cortisol levels with the risk of preterm delivery. This study used a case-control design conducted at Sanglah Hospital, Denpasar from May to August 2021. A sample of 50 women was obtained which was divided into case groups and control groups. Serum cortisol examination used a 3 mL blood sample which was then examined using the ELISA method at the Integrated Biomedical Laboratory, Faculty of Medicine, Udayana University. The results were analyzed using the chi square test. There was no significant difference in the characteristics of the two groups. There was a significant relationship between high serum cortisol levels and the incidence of preterm labor in pregnant women (p < 0.001; 95% CI; 2.768-38.22; OR 10.29). High cortisol serum levels can increase the risk of preterm labor 10 times in pregnant women when compared to pregnant women with low cortisol blood serum levels.
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