Titanium dioxide (TiO 2 ) nanostructures including nanopores and nanotubes have been fabricated on titanium (Ti)-based orthopedic/ dental implants via electrochemical anodization (EA) to enable local drug release and enhanced bioactivity. EA using organic electrolytes such as ethylene glycol often requires aging (repeated anodization of nontarget Ti) to fabricate stable well-ordered nanotopographies. However, limited information is available with respect to its influence on topography, chemistry, mechanical stability, and bioactivity of the fabricated structures. In the current study, titania nanopores (TNPs) using a similar voltage/time were fabricated using different ages of electrolyte (fresh/0 h to 30 h aged). Current density vs time plots of EA, changes in the electrolyte (pH, conductivity, and Ti/F ion concentration), and topographical, chemical, and mechanical characteristics of the fabricated TNPs were compared. EA using 10−20 h electrolytes resulted in stable TNPs with uniform size and improved alignment (parallel to the underlying substrate microroughness). Additionally, to evaluate bioactivity, primary human gingival fibroblasts (hGFs) were cultured onto various TNPs in vitro. The findings confirmed that the proliferation and morphology of hGFs were enhanced on 10−20 h aged electrolyte anodized TNPs. This pioneering study systematically investigates the optimization of anodization electrolyte toward fabricating nanoporous implants with desirable characteristics.
Rationale:In this report, a combination of socket-shield technique (SST) and platelet-rich fibrin (PRF) technique was used for immediate implant placement on a fractured central incisor. During the follow-up visit, cone beam computed tomography (CBCT) and clinical observation were used to evaluate the preservation outcome of peri-implant bone and gingiva.Patient concerns:The patient was a 28-year-old healthy female patient who desired her fractured 21 to be replaced with an implant-supported single crown; the fractured 21 comprised a post-core crown with insufficient residual bone at the labial site.Diagnosis:The root of 21 exhibited a complex root fracture; the labial portion of the alveolar ridge was thin (<1 mm) and partial ankylosis of the residual root was observed.Interventions:Modified SST was applied to the labial portion of the residual root. The implant was placed immediately at the lingual site of the retained socket-shield root fragment; PRF was the placed in the gap between the root fragment and the implant. Final prosthodontic treatment was performed at 24 weeks after implant placement.Outcomes:Clinical examination and CBCT scanning at various follow-up visits time showed that the periodontal tissue was well- preserved. At 6 months after surgery, the average horizontal and vertical peri-implant bone resorption was 0.4 mm; a follow-up visit at 18 months post-loading indicated that peri-implant tissue was well preserved by the shield-technique and no significant peri-implant tissue resorption was displayed.Lesson Subsections:In cases of anterior teeth with intact but insufficient residual alveolar ridge, the SST with PRF may be effective for preservation and maintenance of stable peri-implant tissue.
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