A prospective cohort study was conducted in 315 mother-newborn dyads from Valdivia, Chile. A questionnaire was administered to mothers before 48 hours postpartum, and sociodemographic, obstetric, and neonatal data were collected. At 3 months postpartum, a follow-up by telephone interview or home visit was made, determining the proportion of mothers providing exclusive breastfeeding. Multivariate logistic regression was carried out to identify variables significantly associated with exclusive breastfeeding. Follow-up data showed 98.1% were breastfeeding, and exclusive breastfeeding reached 69.5%. Withdrawal of exclusive breastfeeding was positively associated with single marital status (odds ratio, 2.49; 95% confidence interval: 1.48-4.20) and smoking during pregnancy (odds ratio, 2.61; 95% confidence interval: 1.48-4.60), while maternal education greater than 8 years was associated with continuation of exclusive breastfeeding (odds ratio, 0.45; 95% confidence interval: 0.24-0.84). Breastfeeding education strategies addressed to high-risk pregnant women (single with a low education level) must be emphasized in addition to prevention of nonhealthy habits, such as tobacco and alcohol consumption during gestation.
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