Article history Immunological deficiency observed during the transition period in dairy cows promotes development of puerperal diseases. Thus, the research aimed to evaluate hematological (leukogram) and biochemical (glucose, fibrinogen, and total proteins) parameters in Holstein cows (n = 44) before (day-20) and after (day +20) parturition and the possibility of identifying initial signs of reproductive illness, thereby assisting the professional in decision making. There was a difference in the number of total leukocytes, which decreased postpartum (8,888.4 cells/mm 3). There was no difference in neutrophils at both time points. Females who presented high concentration of fibrinogen (5.2 g/L) and total plasmatic proteins (78.9 g/L) at postpartum presented retention of fetal appendages and later uterine disease. These results are consistent with the literature on antepartum leukocytosis and inflammation indicated by increased fibrinogen and plasmatic protein and differ in terms of neutrophil behavior. Thus, laboratory assays can be complementary tools to physical examination, aiding in the diagnosis and identification of changes even before the appearance of clinical signs in animals, which is necessary for the prevention of metabolic and infectious disorders.
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