Pharmacists applied deprescribing, which is a process for the rational use of drugs, for 13 at-home patients. The standard used for the rational use of drugs was the``Guidelines for Medical Treatment and Its Safety in the Elderly'' (the Guidelines). The results of the deprescribing were discussed with physicians to determine prescriptions. After the prescription change, activities of daily living (ADL) and QOL were assessed using the Barthel Index and SF-36v2, respectively. Potentially inappropriate medications (PIMs) were detected in 10 of the 13 patients (76.9%). This detection rate is higher than previous PIM detection rates of 48.4% and 40.4% reported in prescriptions for home-care patients in Japan under the Beers and STOPP/START criteria. The Guidelines appeared useful as a decision support tool for deprescribing. The patients continuing the changed prescriptions showed no decrease in ADL or QOL after deprescribing, suggesting its rationality. The 10 measurement items of the Barthel Index were all suitable for evaluating the physical conditions of the patients. Meanwhile, SF-36v2 includes many items, but few indexes were directly applicable.Key words-deprescribing; potentially inappropriate medication; home-care patient; activities of daily living; QOL; criteria One agent less as physician prescribed a compounding drug. Vol. 137 No. 5 (2017) 628 628 YAKUGAKU ZASSHI Vol. 137 No. 5 (2017) 3. 薬剤師が作成した処方変更提案及び医師との
YAKUGAKU ZASSHI
協議結果Step 1 において抽出された 13 薬剤の 中止と 1 薬剤の用量変更は,すべて受け入れられた.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.