Global warming-induced climate change evolved to be one of the most important research topics in Earth System Sciences, where remote sensing-based methods have shown great potential for detecting spatial temperature changes. This study utilized a time series of Landsat images to investigate the Land Surface Temperature (LST) of dry seasons between 1989 and 2019 in the Bac Binh district, Binh Thuan province, Vietnam. Our study aims to monitor LST change, and its relationship to land-cover change during the last 30 years. The results for the study area show that the share of Green Vegetation coverage has decreased rapidly for the dry season in recent years. The area covered by vegetation shrank between 1989 and 2019 by 29.44%. Our findings show that the LST increase and decrease trend is clearly related to the change of the main land-cover classes, namely Bare Land and Green Vegetation. For the same period, we find an average increase of absolute mean LST of 0.03 °C per year for over thirty years across all land-cover classes. For the dry season in 2005, the LST was extraordinarily high and the area with a LST exceeding 40 °C covered 64.10% of the total area. We expect that methodological approach and the findings can be applied to study change in LST, land-cover, and can contribute to climate change monitoring and forecasting of impacts in comparable regions.