Graphene
sensitization of glucose-imprinted polymer (G-IP)-coated
optical fiber has been introduced as a new biosensor for evanescent
wave trapping on the polymer optical fiber to detect low-level glucose.
The developed sensor operates based on the evanescent wave modulation
principle. Full characterization via atomic force microscopy (AFM),
Fourier transform infrared (FTIR) spectroscopy, X-ray diffraction
(XRD), scanning electron microscopy (SEM), Raman spectroscopy, high-resolution
transmission electron microscopy (HRTEM), and N
2
adsorption/desorption
of as-prepared G-IP-coated optical fibers was experimentally tested.
Accordingly, related operational parameters such as roughness and
diameter were optimized. Incorporating graphene into the G-IP not
only steadily promotes the electron transport between the fiber surface
and as-proposed G-IP but also significantly enhances the sensitivity
by acting as a carrier for immobilizing G-IP with specific imprinted
cavities. The sensor demonstrates a fast response time (5 s) and high
sensitivity, selectivity, and stability, which cause a wide linear
range (10–100 nM) and a low limit of detection (LOD = 2.54
nM). Experimental results indicate that the developed sensor facilitates
online monitoring and remote sensing of glucose in biological liquids
and food samples.
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