Motivation: The continued progress in developing technological platforms, availability of many published experimental datasets, as well as different statistical methods to analyze those data have allowed approaching the same research question using various methods simultaneously. To get the best out of all these alternatives, we need to integrate their results in an unbiased manner. Prioritized gene lists are a common result presentation method in genomic data analysis applications. Thus, the rank aggregation methods can become a useful and general solution for the integration task.Results: Standard rank aggregation methods are often ill-suited for biological settings where the gene lists are inherently noisy. As a remedy, we propose a novel robust rank aggregation (RRA) method. Our method detects genes that are ranked consistently better than expected under null hypothesis of uncorrelated inputs and assigns a significance score for each gene. The underlying probabilistic model makes the algorithm parameter free and robust to outliers, noise and errors. Significance scores also provide a rigorous way to keep only the statistically relevant genes in the final list. These properties make our approach robust and compelling for many settings.Availability: All the methods are implemented as a GNU R package RobustRankAggreg, freely available at the Comprehensive R Archive Network http://cran.r-project.org/.Contact: vilo@ut.eeSupplementary information Supplementary data are available at Bioinformatics online.

Abstract. Gathering and processing sensitive data is a difficult task. In fact, there is no common recipe for building the necessary information systems. In this paper, we present a provably secure and efficient general-purpose computation system to address this problem. Our solution-SHAREMIND-is a virtual machine for privacy-preserving data processing that relies on share computing techniques. This is a standard way for securely evaluating functions in a multi-party computation environment. The novelty of our solution is in the choice of the secret sharing scheme and the design of the protocol suite. We have made many practical decisions to make large-scale share computing feasible in practice. The protocols of SHAREMIND are information-theoretically secure in the honest-but-curious model with three computing participants. Although the honest-but-curious model does not tolerate malicious participants, it still provides significantly increased privacy preservation when compared to standard centralised databases.

Abstract. In mining and integrating data from multiple sources, there are many privacy and security issues. In several different contexts, the security of the full privacy-preserving data mining protocol depends on the security of the underlying private scalar product protocol. We show that two of the private scalar product protocols, one of which was proposed in a leading data mining conference, are insecure. We then describe a provably private scalar product protocol that is based on homomorphic encryption and improve its efficiency so that it can also be used on massive datasets.

Abstract. Solutions for an easy and secure setup of a wireless connection between two devices are urgently needed for WLAN, Wireless USB, Bluetooth and similar standards for short range wireless communication. All such key exchange protocols employ data authentication as an unavoidable subtask. As a solution, we propose an asymptotically optimal protocol family for data authentication that uses short manually authenticated out-of-band messages. Compared to previous articles by Vaudenay and Pasini the results of this paper are more general and based on weaker security assumptions. In addition to providing security proofs for our protocols, we focus also on implementation details and propose practically secure and efficient sub-primitives for applications.