The aim of this study is to analyze the correlation between the ratio of LH and FSH levels with LDL and HDL cholesterol in PCOS patients. This study is an observational cross-sectional study. The population in this study were women newly diagnosed with polycystic ovary syndrome who came to RSIA Ferina, RSIA Lombok 22, Elizabeth Clinic and RSIA Putri Surabaya and Clinical Pathology Laboratory of dr. Soetomo Surabaya. Examination of FSH, LH and LDL and HDL cholesterol levels on 27 specimens (stored frozen serum) using the ICT (Accurate Intan Madya ® , VEDALAB) and enzymatic colorimetric (Dimension EXL ® , Siemens) methods. Statistical analysis was performed using the Spearman and Pearson correlation test, with a significance level of p <0.05. The results showed that there was a moderate positive correlation between FSH and LDL cholesterol (r = 0.491, p = 0.009). Phenotype D of PCOS (non-hyperandrogenic type) had a moderate negative correlation between the LH / FSH ratio and the LDL/HDL cholesterol level ratio (r = -0.487, p <0.05). However, there was no relationship between the LH/FSH ratio and the ratio of LDL/HDL cholesterol levels in all SOPK patients in this study. This study showed that phenotype D PCOS patients (non-hyperandrogenic type) were less likely to have cardiovascular complications than other phenotypic PCOS patients. Insulin resistance has a role in the risk of dyslipidemia in non-hyperandrogenic PCOS patients.
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