Snakebite is a common medical emergency in the tropics, causing multisystemic involvement. Ophthalmic manifestations after snakebite have included ptosis and ophthalmoplegia. Uveitis as an immunological complication following therapy with anti-snake venom (ASV) serum has been rarely reported in literature.We reported two patients who developed uveitis and acute renal failure following snakebite treatment with ASV serum. Both patients recovered uneventfully with appropriate therapy.
Generally among the branches of common peroneal nerve, the superficial peroneal nerve provides cutaneous innervation to major part of the dorsum of the foot whereas the deep peroneal nerve innervates the skin over the first interdigital cleft region. The sural and saphenous nerves supplies the smaller lateral and medial margins of the dorsum respectively. The present study has been taken to classify the patterns of innervations of the nerves on the dorsum of the foot in South Indian population. A total of 40 formalin fixed lower limbs from 20 adult cadavers (15 males, 5 females) aged between 35 to 60 years were dissected and the branching patterns of nerves on the dorsum of the foot were noted and specimens were photographed. Gross anatomical variations were noted in the branching pattern of superficial peroneal, deep peroneal and sural nerve on the dorsum of foot. Results obtained in our study were classified into four groups. The cutaneous nerves are at risk of iatrogenic injuries during surgeries involving ankle, open reduction and internal fixation of fracture, arthroscopy etc. Knowledge of such anatomical variations of the nerves provides information to clinicians to avoid injury to them in real clinical situations.
Tuberculosis (TB) continues to be a major opportunistic infection after renal transplantation especially in the tropical countries. The risk of TB in renal transplant recipients is reported to be 20-74 times higher than that in the general population. Genitourinary TB that occurs after renal transplantation in uncommon and appears to present differently than genitourinary TB in the nontransplant population. An increased risk of graft rejection and graft loss has been reported. We report three cases of genitourinary TB in renal transplant recipients, all of whom had a good clinical outcome and a review of published literature.
Stroke is considered to be one of the most important causes of death worldwide. Global ischemia causes widespread brain injury and infarctions in various regions of the brain. Oxidative stress can be considered an important factor in the development of tissue damage, which is caused because of arterial occlusion with subsequent reperfusion. Kapikacchu or Mucuna pruriens, commonly known as velvet bean, is well known for its aphrodisiac activities. It is also used in the treatment of snakebites, depressive neurosis, and Parkinson's disease. Although this plant has different pharmacological actions, its neuroprotective activity has received minimal attention. Thus, this study was carried out with the aim of evaluating the neuroprotective action of M. pruriens in bilateral carotid artery occlusion-induced global cerebral ischemia in Wistar rats. The carotid arteries of both sides were occluded for 30 min and reperfused to induce global cerebral ischemia. The methanolic plant extract was administered to the study animals for 10 days. The brains of the Wistar rats were isolated by decapitation and observed for histopathological and biochemical changes. Cerebral ischemia resulted in significant neurological damage in the brains of the rats that were not treated by M. pruriens. The group subjected to treatment by the M. pruriens extract showed significant protection against brain damage compared with the negative control group, which indicates the therapeutic potential of this plant in ischemia.
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