Calvarial tuberculosis is rare presentation and has been reported in only about 0.01% of all patients with mycobacterial infections. Though rare, the incidence of Calvarial tuberculosis seems to be on the rise, especially in developing countries. We present three cases of Calvarial tuberculosis which were successfully managed at our Centre. All the cases occurred de novo in young, otherwise healthy individuals, hailing from good socio-economic backgrounds and without any past history or contact history with tuberculosis patients. We highlight the importance of keeping this diagnosis in mind in appropriate clinical situations as well as recommend the early commencement of optimal management to prevent serious neurologic complications & sequelae.
Clear-cell meningioma (CCM) is an uncommon, aggressive variant of meningioma, usually affecting younger females and having predilection for infratentorial locations. We present a rare case of recurrent supratentorial CCM in a 58-year-old male. Ten years back, he had an intra-axial tumor in the left occipital lobe, which was managed by surgical excision and radiotherapy. Currently, the patient presented with sudden severe headache along with speech and vision disturbances. Neuroimaging revealed an extra-axial parietooccipital tumor, with intratumoural bleed. Histopathology of both tumors showed features of CCM, immunopositive for epithelial membrane antigen (EMA) and vimentin. This case illustrates multiple unusual features of a rare variant of meningioma in the form of affection of an adult age group, supratentorial location, recurrence, and intratumoral bleed. It also highlights the importance of incorporating immunohistochemistry in the diagnostic workup, to exclude CCM mimics, each having distinctive biological behavior, and prognostic outcome, and warranting different therapeutic protocols.
We present a case report of a young adult male who sustained severe head injury in a bomb blast. He was later detected to have traumatic chiasmal syndrome as well as cerebrospinal fluid rhinorrhoea. There were no other complications associated. He was managed conservatively. A review of the present literature and current understanding of the pathogenesis of this intriguing syndrome is presented. Traumatic chiasmal syndrome must be recognized in cases of head injury which can be associated with life threatening complications.
Inflammatory Myofibroblastic Tumor (IMT) is a rare pathologic entity that was first described in 1973. This lesion is most commonly found in the lungs, but other organs' involvement has also been reported. Intracranial location of Inflammatory Myofibroblastic Tumor is rare, and the first case was reported in 1980. An intriguing fact about the intracranial IMT is its resemblance with meningioma on clinical presentation and neuroimaging. We came across a case of intracranial Inflammatory Myofibroblastic Tumor (IIMT) in a 27-year-old male who presented with recurrent episodes of seizures and was diagnosed as meningioma on neuroimaging. The lesion did not subside with medical management and kept on progressing in size. The patient had to undergo surgery, and diagnosis of Inflammatory Myofibroblastic Tumor was ascertained on histopathology. This 'surprise' diagnosis prompted us to review the literature on all cases of IIMTs reported to date to better understand the entity and its implications. In this review article, we present our observations regarding various studied parameters, including patient profile, clinical presentation, site of involvement, focality of the lesion, special associations, and lines of management of the 49 published cases of IIMTs.
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