Introduction: The COVID-19 pandemic has a major negative impact on health and socio-economic well-being. Understanding the characteristics of COVID-19 disease and identifying the wide range of factors affecting health and quality of life can be the key to providing viable solutions to improve the management of patients and their physical and psycho-emotional rehabilitation. The purpose of the present study was to evaluate the influence of SARS CoV-2 infection on the health status of adults hospitalized with the diagnosis of COVID-19 in the Republic of Moldova. Material and methods: The presented study is a retrospective, cohort, consisting of a sample of 7441 patients randomly selected, aged 18 y.o. and older, hospitalized in 10 public medical institutions in Chisinau, Moldova. Diagnosis of COVID-19 was confirmed by detection of CoV-2 SARS RNA. The data in the patients’ medical records were processed and stored according to the unified, pre-established form, prepared in accordance with the requirements of the software „Electronic Patient Record COVID-19”. The severity of COVID-19 disease was assessed using two principles: (1) according to the criteria of the National Clinical Protocol PCN-371; (2) according to the 7-point graduated scale developed by the WHO Special Committee (V.3.0, 3 March 2020) in randomized multicenter clinical trials. Result: Only 30.07% patients mentioned the presence of a close contact with a COVID-19 positive person. The average age of the patients in the study was 52.83 years. Mild form was diagnosed in 5.00% of patients, medium - 66.15%, severe –20.67%, critical-8.18%. The main complaints of patients were fever, fatigue or physical asthenia, cough, and headache. More than 1/4 of those hospitalized have severe or critical forms of COVID-19; more than 1/3 - require oxygen therapy, and every 6-th patient needs non-invasive high-flow oxygen ventilation or mechanical ventilation. Old age, male sex, chronic comorbidities increase statistically significantly the probability of patients having an unfavorable prognosis in COVID-19. 7.93% of patients died, according to the age group: every 2-nd patient over 90 years, every 3-rd over 80 years, every 5-th over 70 years, and every 9-th over 60 years died. Conclusions: (1) The uncertainty of the source of infection lead to delay specific prophylactic public health measures; (2) In COVID-19, in a hospital-type medical management, the emphasis should be placed mainly on patients over the age of 50; (3) There is no specific clinical manifestation in COVID-19, that would allow to distinguish the disease from other pathologies; (4) Age over 60 y.o., male sex, and chronic cardiovascular diseases, diabetes mellitus, chronic kidneys diseases and malignant tumors unfavorable influence the evolution of COVID-19; (5) Antibiotic administration remains at a high level in hospitalized patients and is often unjustified and unnecessary.
Form represents the external aspect, the appearance under which any thing or object in the surrounding world is presented. In the fine arts, form is the result of the creative process and includes the idea or concept that underlies the masterpiece. Depending on the configurations of the form, it acts directly on the perception, accessing the associative - intuitive levels of memory through special psychic mechanisms. Any form corresponds to a certain semantic and emotional meaning. The language of visual forms is a universal, symbolic, figurative or abstract language, multiple and very diverse in terms of treatment and plastic expression. The form through its pronounced evaluative-associative properties and aspects represents a strong means of communication, often not consciously needed. Graphic and pictorial forms have very diverse associations and symbolic meanings, which are found in universal human thought and constitute the visual grammar of plastic language, used by artists, painters, designers, etc. Visual symbols have their own language, being made up of associations of significant elements of form. The different characteristics of the forms convey different emotions and meanings. These visual forms instantly transmit complex messages by triggering deep psychic reactions. In the process of establishing meaning, any form is analyzed not only by its exterior, but also by its inner essence (internal structure). As a result, through its evaluative-associative aspects, they represent a powerful means of communication, often not consciously needed.
The present study elucidates the presence of the phenomenon of artistic synesthesia in painting, describes the types of synesthesia and their effects, sensory symbiotic relationships, correlations with different genres of art: dance, music, literature. Early art forms were initially distinguished by an archaic and primary syncretism, being interconnected and dependent on each other. Subsequently, during the historical evolution, these artistic forms were dispersed in separate art genres, while preserving this specific intermediarity and interrelation, of artistic synesthesia. Synesthetic phenomena in painting are stylistically interconnected with music, dance, literature.
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