Endobronchial ultrasound (EBUS) and real-time guidance of transbronchial needle aspiration (TBNA) has become a widely adopted tool in evaluation of intrathoracic lymphadenopathy for malignant or non-malignant disease. EBUS has been shown to have comparable diagnostic yield and safety profile when done with either moderate sedation (MS) or deep sedation (DS). The purpose of this study was to assess the use of diphenhydramine in bronchoscopies and specifically EBUS/TBNA. METHODS: Patient data was collected via chart review of all bronchoscopies done at the Kansas City VA Medical Center between July 2018 and June 2019. Only procedures done under MS were included. Sedation medications used were fentanyl and midazolam. The use of intravenous diphenhydramine, dose and timing was at the discretion of the proceduralist.
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