The RMI is an appropriate method in diagnosing adnexal masses with high risk of malignancy and forwarding to gynecological oncology centers for suitable surgical operations.
<b><i>Objectives:</i></b> The aim of the study is to investigate the predictive value of ischemia-modified albumin (IMA) as an oxidative stress indicator in renal ischemia-reperfusion (I/R) injury. <b><i>Methods:</i></b> Forty female Wistar Albino rats were divided into 5 groups: Group-1, sham; group-2, 20 min I/R, group-3, 30 min I/R; group-4, 40 min I/R; and group-5, 60 min I/R. Blood samples were taken, and nephrectomy was performed in the sham group before ischemia was induced. At the end of the defined periods for each group, reperfusion was achieved and a blood sample was taken and nephrectomy was performed. At the end of the 6-hour reperfusion period, the blood sample was taken again and the other kidney is removed. IMA in serum and total anti-oxidant status (TAS), total oxidant status (TOS), and oxidative stress index in both serum and tissue were examined. <b><i>Results:</i></b> Serum IMA values were significantly different between the groups (<i>p</i> = 0.009), and there was a significantly difference in TOS values between ischemic serum (<i>p</i> = 0.024) and tissue samples (<i>p</i> = 0.02). However, there was no significant difference in serum and tissue TAS values after ischemia (<i>p</i> = 0.9). Serum IMA, TOS and TAS and tissue TOS and TAS values after reperfusion were not significantly different. There was a significant correlation between tubular damage and ischemia duration in histopathological examination of renal tissue after I/R (<i>p</i> < 0.0001). <b><i>Conclusion:</i></b> Serum IMA values increased in parallel with the duration of ischemia, and this increase was supported by histopathological damage findings.
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