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Background China has the world’s largest population, going under health transition due to industrialization, urbanization, and a sedentary lifestyle. About 82% of China’s disease burden is due to the prevalence of non-communicable diseases (NCDs). Physical activity (active travel) is the best preventive measure against NCDs. The Chinese government has introduced several steps to improve national fitness and overcome NCDs among the aging population. Exercise and sports play a vital role in promoting physical activity and helpful in accomplishing the national fitness level for Healthy China under the national fitness plan (NFP). Objective The current study aimed to explore the role of national fitness plan (NFP) in promoting physical activity and health well-being preventing NCDs under built environment intervention. Methods The study was exploratory, and the mixed-method approach was used to analyze the primary and secondary data. Quantitative content analysis was used to analyze the collected data. A purposive sampling technique was used to collect the primary data from those individuals rich in knowledge about the National Fitness Plan (NFP) of China and its role in promoting physical activity for physical fitness. Results The majority of the participants (32.0%) said that the national fitness plan helps promote sports environment and health. About 28.0% reported that NFP helps promote cycling and walk environments for physical activity and health promotion and preventing non-communicable diseases (NCDs). Conclusion Participation in physical exercise and sports is the preferred approach to prevent different diseases. In the context of rising active living among the Chinese people, the facilities such as built environment and green parks under the national fitness plan (NFP) for sports play a crucial role in the mitigation of NCDs.

Massive multiple-input multiple-output or massive MIMO system has great potential for 5th generation (5G) wireless communication systems as it is capable of providing game-changing enhancements in area throughput and energy efficiency (EE). This work proposes a realistic and practically implementable EE model for massive MIMO systems while a general and canonical system model is used for single-cell scenario. Linear processing schemes are used for detection and precoding, i.e., minimum mean squared error (MMSE), zero-forcing (ZF), and maximum ratio transmission (MRT/MRC). Moreover, a power dissipation model is proposed that considers overall power consumption in uplink and downlink communications. The proposed model includes the total power consumed by power amplifier and circuit components at the base station (BS) and single antenna user equipment (UE). An optimal number of BS antennas to serve total UEs and the overall transmitted power are also computed. The simulation results confirm considerable improvements in the gain of area throughput and EE, and it also shows that the optimum area throughput and EE can be realized wherein a larger number of antenna arrays at BS are installed for serving a greater number of UEs.

Objectives: To investigate the occurrence and molecular features of ESBL-producing and colistin-resistant Escherichia coli isolates recovered from healthy food-producing animals in Pakistan. Methods: A total of 153 E. coli isolates were recovered from 250 faecal samples collected from livestock and poultry. The antibiotic susceptibility, resistant determinants and mobile genetic elements were determined for all the isolates. The clonal relatedness was analysed by MLST. Plasmids harbouring, localization and transferability of mcr-1 gene were carried out by Southern hybridization, S1-PFGE and transconjugation.Results: Out of 153 E. coli strains, 49.01% isolates were ESBLs producers, whereas 18.95% were resistant to colistin and 84.31% of the isolates. Multidrug resistance was found in 84% of the isolates. The ESBL-producing E. coli in buffaloes, cattle, sheep, goat and broilers faecal samples were 60%, 74%, 54%, 50% and 68%, respectively. Among the ESBLs genes, bla CTX-M was the most prevalent group detected in 98.66%, while only mcr-1 of the colistin-resistant genes could be PCR amplified in 29 isolates. The common MGEs found were ISECP1 (35.13%), ISCR1 (33.78%), ISApl1 (20.27%) and Inti1 (58.10%). The most predominant Inc. types found were IncFIB 46.66%, followed by IncFIA 30.66%, IncFIC 26.66%, IncFrepB 26.66%, IncHI2 26.66%, IncP 22.66% and IncX4 21.33%. The most frequent sequence type detected was ST58.Southern blot and S1-PFGE confirmed the plasmid harbouring of mcr-1 gene. Conclusion:The co-occurrence of mcr-1 and ESBLs-encoding genes, along with MGEs in E. coli from healthy food animals in Pakistan, is a major concern.