Two cats were presented with vestibular signs and seizures. Both cats were diagnosed with thiamine deficiency. The transverse and dorsal T2-weighted magnetic resonance (MR) images revealed the presence of bilateral hyperintense lesions at specific nuclei of the midbrain, cerebellum, and brainstem. After thiamine supplementation, the clinical signs gradually improved. Repeated MR images taken 3 weeks after thiamine supplementation had started showed that the lesions were nearly resolved. This case report describes the clinical and MR findings associated with thiamine deficiency in two cats.
In patients with knee OA, SPECT findings are well correlated with clinical findings, such as pain scores and physical examinations, and SPECT appears to be a sensitive tool for early detection of knee OA. SPECT information could be useful for determining clinical severity of knee OA and for diagnosing early OA more effectively.
ABSTRACT. A 6-year-old ShihTzu presented with tonic-clonic cluster seizure. T2-weighted magnetic resonance (MR) images showed bilateral diffuse hyperintense lesions at the cerebral cortex with enlarged sulci. Computed tomography revealed a portosystemic shunt (PSS) and azygos continuation. Based on the clinical signs, blood examinations and diagnostic images, the dog was diagnosed with hepatic encephalopathy secondary to PSS. The neurologic signs were gradually improved after medical therapy for hyperammonemia. This is the first report of hyperintensity of the cerebral cortex on T2-weighted MR images associated with acute hepatic encephalopathy in a dog.
AbSTRAcT. A 7-year-old, 1.76 kg Maltese dog presented with a 4-year history of a chronic pustular lesion and a wet cough. Erosive lesions were seen at the left thoracic wall. Radiology and computed tomography (CT) revealed a bronchocutaneous fistula connecting from the left cranial bronchus to the skin. On definitive surgery, a long wooden toothpick was observed within this tract, and clinical signs resolved after retrieval of the foreign body. Three-dimensional cT was useful to identify the characteristics of the bronchocutaneous fistula. However, the wooden foreign body was not apparent on CT. Here, we report the clinical, clinicopathological and diagnostic imaging findings of a chronic bronchocutaneous fistula caused by a foreign body in a dog. A fistula is a draining tract and a pathological connection between body organs and cavities [2,6]. Most fistulas are associated with a foreign body, most commonly a wooden object [8]. Fistulas associated with foreign bodies in dogs involve the esophagoaortic, esophagotracheal, esophagobronchial, gastrocutaneous and cutaneopulmonary tracts [2,5,9,12]. Numerous cases of bronchocutaneous fistulas have been reported in humans, which develop as a complication of infection [3,4], chest tube placement [6], lung lobectomy [7], mechanical ventilation [1], or epicardial pacing [10]. In veterinary medicine, an uncommon case of bronchocutaneous fistula with unknown etiology in a large breed of dog has been reported [11]. The clinical manifestations were very similar to those of a dog with a cutaneopulmonary fistula associated with a foreign body [5]. However, no cases of a bronchocutaneous fistula caused by a foreign body diagnosed by cT have been reported in a small breed dog.This case report demonstrated the clinical, clinicopathological, and diagnostic imaging findings of a bronchocutaneous fistula within a long wooden toothpick in a dog.A 7-year-old, 1.76 kg, intact female Maltese dog presented due to a chronic and recurrent pustular lesion over the left thoracic wall and a productive cough during the past 4 years. The lesion had not improved despite the use of various medications and surgical excisions. In the past, the dog was a stray and had been adopted by the present owner from an animal shelter. Upon physical examination, two erosive lesions with purulent discharge at the left thoracic wall were observed (Fig. 1A). Other vital signs including body temperature, heart rate and respiration rate were normal. A thoracic auscultation revealed normal heart sounds and pulmonary fields. A complete blood count was normal. Serum biochemical examination revealed mild hyperglobulinemia with normal albumin level (globulin 4.5 g/dl, reference range 2.5-4.0 g/dl). Routine thoracic radiographs demonstrated a soft tissue-density of tubular structure in the left lung lobe, with the caudal part consisting of the skin lesions ( Fig. 2A and 2b). No evidence of pleural effusion or pneumothorax was noted. A purulent discharge from the erosive lesions was revealed as a neutrophilic inflammation...
ABSTRACT. A 14-year-old Maltese dog presented for complete medical examination due to intermittent vomiting and diarrhea observed during the previous two days. A single, solitary, lobulated cystic mass was observed in the liver upon ultrasonographic and computed tomographic examination. After surgical hepatic resection to remove the mass, histological examination revealed a multilocular cyst lined by cuboidal to columnar epithelial cells, which is consistent with biliary cystadenoma. Here, we report the clinical, clinicopathological, histopathological, and diagnostic imaging findings of biliary cystadenoma in a dog.KEY WORDS: biliary cystadenoma, canine, liver.J. Vet. Med. Sci. 73(12): 1677-1679, 2011 Biliary cystadenoma is benign cystic tumor arising from biliary epithelium that most frequently occurs in the intrahepatic bile duct [3,4]. Biliary cystadenoma is a less common cystic lesion of the liver in humans and is referred to as cystadenoma, bile duct adenoma or cystic cholangioma [3,7]. In humans, although accurate etiology is unclear, biliary cystadenoma is known as benign hepatic tumor. However, it is also referred to as a premalignant lesion because of the risk of malignant changes. The clinical signs of biliary cystadenoma are usually unspecific or absent, and diagnosis is made from diagnostic imaging and histopathologic examination. Histological features of biliary cystadenoma in humans consist of a multilocular cyst lined with cuboidal to columnar epithelial cells and cellular stroma [4]. Biliary cystadenoma should be differentiated with other hepatic cystic lesions including cystadenocarcinoma, hematoma or hepatic simple cyst [7,8]. There have been numerous case reports of biliary cystadenoma in humans [3,7,8] and cats [1,5,6,9]; however, there have been no reports of its occurrence in dogs. According to veterinary literature, most of clinical manifestations in cats are similar to those in humans, but the histologic features are somewhat different in that the tumor consists of noncellular septa [1,5,6,9]. Here, we describe the clinical, clinicopathological, histopathological, and diagnostic imaging findings of biliary cystadenoma in a dog.A 14-year-old, castrated male Maltese dog presented due to intermittent vomiting and diarrhea observed the previous two days. One month prior to presentation, the dog was treated with pancreatitis, at which time a hepatic mass was detected incidentally upon ultrasonographic examination at local animal hospital. Upon physical examination, the patient was mildly depressed and abdominal distension was showed. No palpable abdominal mass was detected, and, mild abdominal pain, especially on the right upper part was suspected. The results of complete blood counts revealed mild leukocytosis (white blood cell [WBC] 9.1 U/l, reference range, 0-6) and bile acid levels (postprandial 47.7 μmol/l, reference range, <25.0 μmol/l). Lipase (92 U/l, reference range, 0~500) and bilirubin (0.13 U/l, reference range, 0.1~0.4) levels were normal. Electrolytes, acidbase and coagulation ...
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