Background: Sigmoid volvulus occurs when the sigmoid colon twists on its mesentery and is a cause of intestinal obstruction. Method: This was a descriptive study conducted at the Surgery department of Rajshahi Medical College Hospital during the period from May 2009 to June 2011. Ethical consideration was taken from all the patients. The sample size was 50 with acute sigmoid volvulus. Data were processed and analyzed through SPSS (Statistical package for social sciences). A value of p ≤0.05 was considered significant statistically. Result: Most patients (56%) were diagnosed with acute sigmoid volvulus from the age range of 51-60, among whom male patients had a prevalence (92%). Most of them (92%) were economically impoverished. 36% of patients came to the hospital for treatment from 37-48 hours of illness. The post-operative complication was mild due to wound infection in 10% of patients. Hospital stay was 8-10 days for 76% of patients without complications postoperatively and 11-13 days for 14% of patients. Severe complication Resulting in hospital stay was seen in 4% of patients. Conclusion: Emergency resection of the sigmoid colon and anastomosis in unprepared bowel was an attractive and preferred option in a setting where patients are poor, hospital care often unaffordable and hospital beds are few. TAJ 2022; 35: No-2: 13-18
Introduction: Splenectomy has long been used to treat benign hematological abnormalities such as immune thrombocytopenia (ITP), some hemolytic anemias- especially hereditary spherocytosis and thalassemia, and prehepatic portal hypertension. The discovery that splenectomized individuals are more vulnerable to encapsulated organism infection has been attributed to the spleen's lack of filtration and the development of anticarbohydrate antibodies. Recent research in such splenectomized patients suggests that the lack of this specific anticarbohydrate antibody in these participants is attributable to a decreased number of Memory B cells (a subgroup of B lymphocytes in charge of T-independent responses). Traditional vaccinations, which are given to splenectomized patients to protect them from being infected by encapsulated organisms, can only act in the presence of both the spleen and its functioning marginal zone. As a Result, the study will look at the level of memory B cells in the blood after three months and 1-year post-splenectomy. Aim of the study: The objective of the study was to observe the short- and long-term effects of splenectomy on memory B cells in children. Methods: This prospective case-control study was conducted at the Pediatric Surgery Department of Bangabandhu Sheikh Mujib Medical University, Bangladesh. The study duration was one year, from July 2015 to August 2016. A total of 26 children were selected through a purposive sampling technique for this study, where the control group consisted of 10 children, and the case group consisted of 16 splenectomized children. Result: Among the case group participants, 56.25% were from the oldest age group of 12-15 years, and 37.5% were from the age group of 8-11-years. Male prevalence was high in both the control and the case group. Beta thalassemia was the primary indication for splenectomy for 81.25% of case group patients. Mean B lymphocyte was 39700.2 in the control group, 3655.3 at the 3-month follow-up of case group participants, and 3381.7 for those who had follow-up1-year after splenectomy. The mean amount of IgM memory B cells in the control group was 17.92%; at the 3-month follow-up of the case, it was 18.96%, and at the 1-year follow-up, it was 4.34%. Conclusion: In post-splenectomy individuals, immunological constitutions in memory B cells do not support a T-independent response and, therefore, vaccination. TAJ 2022; 35: No-1: 39-44
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.