No abstract

Crowd counting is a challenging task, mainly due to the severe occlusions among dense crowds. This paper aims to take a broader view to address crowd counting from the perspective of semantic modeling. In essence, crowd counting is a task of pedestrian semantic analysis involving three key factors: pedestrians, heads, and their context structure. The information of different body parts is an important cue to help us judge whether there exists a person at a certain position. Existing methods usually perform crowd counting from the perspective of directly modeling the visual properties of either the whole body or the heads only, without explicitly capturing the composite body-part semantic structure information that is crucial for crowd counting. In our approach, we first formulate the key factors of crowd counting as semantic scene models. Then, we convert the crowd counting problem into a multi-task learning problem, such that the semantic scene models are turned into different sub-tasks. Finally, the deep convolutional neural networks are used to learn the sub-tasks in a unified scheme. Our approach encodes the semantic nature of crowd counting and provides a novel solution in terms of pedestrian semantic analysis. In experiments, our approach outperforms the state-of-the-art methods on four benchmark crowd counting data sets. The semantic structure information is demonstrated to be an effective cue in scene of crowd counting.

Microrobots driven by multiple propelling forces hold great potential for noninvasively targeted delivery in the physiologic environment. However, the remotely collective perception and precise propelling in a low Reynold’s number bioenvironment remain the major challenges of microrobots to achieve desired therapeutic effects in vivo. Here, we reported a biohybrid microrobot that integrated with magnetic, thermal, and hypoxia sensitivities and an internal fluorescent protein as the dual reporter of thermal and positioning signals for targeted cancer treatment. There were three key elements in the microrobotic system, including the magnetic nanoparticle (MNP)-loaded probiotic Escherichia coli Nissle1917 (EcN@MNP) for spatially magnetic and hypoxia perception, a thermal-logic circuit engineered into the bacteria to control the biosynthesis of mCherry as the temperature and positioning reporter, and NDH-2 enzyme encoded in the EcN for enhanced anticancer therapy. According to the fluorescent-protein-based imaging feedback, the microrobot showed good thermal sensitivity and active targeting ability to the tumor area in a collective manner under the magnetic field. The cancer cell apoptosis was efficiently triggered in vitro and in vivo by the hybrid microrobot coupled with the effects of magnetothermal ablation and NDH-2-induced reactive oxygen species (ROS) damage. Our study demonstrates that the biohybrid EcN microrobot is an ideal platform to integrate the physical, biological, and chemical properties for collective perception and propelling in targeted cancer treatment.

Capabilities of inference and prediction are the significant components of visual systems. Visual path prediction is an important and challenging task among them, with the goal to infer the future path of a visual object in a static scene. This task is complicated as it needs high-level semantic understandings of both the scenes and underlying motion patterns in video sequences. In practice, cluttered situations have also raised higher demands on the effectiveness and robustness of models. Motivated by these observations, we propose a deep learning framework, which simultaneously performs deep feature learning for visual representation in conjunction with spatiotemporal context modeling. After that, a unified path-planning scheme is proposed to make accurate path prediction based on the analytic results returned by the deep context models. The highly effective visual representation and deep context models ensure that our framework makes a deep semantic understanding of the scenes and motion patterns, consequently improving the performance on visual path prediction task. In experiments, we extensively evaluate the model's performance by constructing two large benchmark datasets from the adaptation of video tracking datasets. The qualitative and quantitative experimental results show that our approach outperforms the state-of-the-art approaches and owns a better generalization capability.

Contrastive learning has been widely applied to graph representation learning, where the view generators play a vital role in generating effective contrastive samples. Most of the existing contrastive learning methods employ pre-defined view generation methods, e.g., node drop or edge perturbation, which usually cannot adapt to input data or preserve the original semantic structures well. To address this issue, we propose a novel framework named Automated Graph Contrastive Learning (AutoGCL) in this paper. Specifically, AutoGCL employs a set of learnable graph view generators orchestrated by an auto augmentation strategy, where every graph view generator learns a probability distribution of graphs conditioned by the input. While the graph view generators in AutoGCL preserve the most representative structures of the original graph in generation of every contrastive sample, the auto augmentation learns policies to introduce adequate augmentation variances in the whole contrastive learning procedure. Furthermore, AutoGCL adopts a joint training strategy to train the learnable view generators, the graph encoder, and the classifier in an end-to-end manner, resulting in topological heterogeneity yet semantic similarity in the generation of contrastive samples. Extensive experiments on semi-supervised learning, unsupervised learning, and transfer learning demonstrate the superiority of our AutoGCL framework over the state-of-the-arts in graph contrastive learning. In addition, the visualization results further confirm that the learnable view generators can deliver more compact and semantically meaningful contrastive samples compared against the existing view generation methods. Our code is available at https://github.com/Somedaywilldo/AutoGCL.