The Brown UniversiTy Child & AdolesCenT PsyChoPhArmACology UPdATe 7 thorough medical evaluation. Parents were also carefully interviewed and were requested to rate the severity of the ADHD-RS-IV symptoms based on the behavior of their children at home. Among the exclusion criteria was use of any medication that might have adverse reactions with saffron, including warfarin, aspirin, other antiplatelet agents, and herbal medicines (such as garlic, feverfew, ginseng, dong quai, red clover, and other natural coumadins). One group received methylphenidate (Ritalin), and the second received saffron capsules.

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