Objective: To study the clinical characteristics and treatment of meningiomas in children. Methods: One hundred and sixty-six meningiomas in children, including 12 cases treated in Qilu hospital and 8 series reported in the literature, were analyzed retrospectively on sex, age distribution, presenting symptoms, signs, radiological and pathological findings, treatment and prognosis. Results: The ratio of boys and girls was 2.3:1. The age ranged from 0.5 to 15 years (mean 9.9 years). Cranial nerve disorder (28%) and signs of chronic increased intracranial pressure such as headaches (62%), vomiting (53%) and papilledema (55%) were the most common symptoms. The most common location was the cerebral convexity (41%), followed by ventricles (15%), saddle areas (8%), cerebellopontine angles (8%), brain intraparenchyma (5%), parasagittal regions (4%), etc. Homogeneous density was observed in 62.3% of all cases, calcification in 14.8%, cystic components in 21.3% and intratumoral hemorrhage in 1.6%. On average, the epithelial and fibroblastic types of meningiomas took up 55% of the case, while the amount of malignant or atypical meningiomas averaged 9%. Complete tumor excision was achieved in 74%, and postoperative mortality was 3.3%. Conclusions: Compared with meningiomas in adults, meningiomas in children occur predominantly in males with a lower incidence rate of epilepsy, and are frequently associated with multiple neurofibromatosis. Meningiomas in children have a poorer prognosis than those in adults. Degree of the first tumor resection, tumor location, pathological grade and association with neurofibromatosis are the most important factors influencing the patients’ prognoses.

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AIm: To evaluate the effectiveness of microvascular-decompression (MVD) or MVD+partial-sensory-rhizotomy (PSR) on the treatment of primary trigeminal neuralgia (TN).mAterIAl and methOds: 210 TN patients were retrospectively studied, among which there're 142 cases underwent MVD and 68 cases underwent MVD+PSR. results:In MVD group, pain vanished in 128, obviously relieved in 9, and 137 cases were profited from MVD. In 82 cases with a follow-up over 2 years, pain vanished in 74, pain sometime occurred in 5 which could be relieved by oral medicine, 3 cases could not be controlled effectively by medicine. In MVD+PSR group, pain completely vanished in 67 cases, not changed in 1 case. In 47 cases with a follow-up over 2 years, pain sometime occurred in 2 which could be relieved by carbamazepine, the others were completely pain-free. The short-term pain-free rate of MVD+PSR group was obviously higher than MVD group(P<0.05), after a follow-up over 2 years, the former was still higher than the later, 95.7% and 90.2% respectively, without significant difference in statistics.COnClusIOn: MVD+PSR was obviously superior to MVD in completely eliminating pain in short-term period after operation, however, longer pain-free rate need even longer time to follow up. Identifying the responsible vascular exactly and handling it reasonably were key to both groups. BulGulAr: Mikrovasküler dekompresyonun uygulandığı 137 hastadan 128'inde ağrı giderilmiş, 9'unda ise ağrıda bariz bir azalma olmuştur. Olguların 82'sinin 2 yıllık takibinde; 74 olguda ağrı görülmedi, 5 olguda nadir ağrı oldu ve oral ilaçlar ile kontrol edilebildi, 3 olgunun ağrısı ise oral ilaçlar ile kontrol edilemedi. Mikrovasküler dekompresyonun yanı sıra parsiyel duyusal rizotomi yapılan hastalardan 67'sinde ağrı görülmedi, 1'inde ağrı değişmedi. Bu olguların 47'sinin 2 yıllık izleminde; 2 olguda ağrı oldu ve karbamazepin ile rahatladı, diğer olgularda ağrı görülmedi. Erken dönemde mikrovasküler dekompresyon+parsiyel duyusal rizotomi yapılan olgularda, sadece mikrovasküler dekompresyon yapılan olgulara göre ağrısız bir dönem elde edilmiştir (P<0.05). İki yıllık sonuçlar incelendiğinde mikrovasküler dekompresyon+parsiyel duyusal rizotomi olgularının % 95,7 sinde ağrı yok iken sadece mikrovasküler dekompresyon yapılan olguların % 90,2'sinde ağrı yoktu; ancak iki grup arasında anlamlı istatistiksel fark bulunmadı. KeywOrds sOnuÇ:Mikrovasküler dekompresyon+parsiyel duyusal rizotomi ile mikrovasküler dekompresyon karşılaştırıldığında: erken dönemde mikrovasküler dekompresyon+parsiyel duyusal rizotomi mikrovasküler dekompresyona daha üstündür; ancak uzun dönemli karşılaştırma yapmak için takip sürelerinin uzatılarak değerlendirme yapılması gereklidir. Her iki grup içinde sorumlu vasküler etiyolojinin çok iyi ortaya konarak incelenmesi gereklidir.

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