Oregano is widely used as aromatics in food and alcohol. Oregano oil has been used in traditional medicine for decades. Oregano essential oil (OEO) is extracted from leaves from the oregano plant. Oregano is known for its antibacterial and antispasmodic properties due to its polyphenol content, which includes many flavones. The aim of the study was to assess the Anti-Inflammatory Potential of Intracanal Medicament Containing Oregano Essential Oil (OEO). The anti-inflammatory activity of an intracanal medicament containing oregano essential oil at various concentrations was evaluated using the raw 264.7 cell line. The ability of extracts to suppress nitric oxide generation by cells was used to calculate percentage inhibition. Curcumin was used as the standard. The study concluded that anti-inflammatory activity of the formulation showed IC50 value of 94.34%, and hence can be used clinically to treat infected root canals.
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