Inflammatory myofibroblastic tumor is an uncommon soft tissue neoplasm of uncertain biologic behavior, and rarely reported in the stomach. An eighteen-year-old male presented with a mass in the epigastrium of three-month duration. Clinical and radiological examination suggested a gastrointestinal stromal tumor or a leiomyoma in the lesser curvature of the stomach. On the basis of histomorphological features and immunohistochemical analysis the diagnosis of inflammatory myofibroblastic tumor in the lesser curvature of the stomach was made. Inflammatory myofibroblastic tumor should be considered in the differential diagnosis of soft tissue tumors of the stomach.
Background: Ovarian tumors account for about 30% of female genital tract tumors and is fourth leading cause of cancer deaths in females. This study was conducted to evaluate the frequency and distribution of histological types of ovarian tumors. Methods: This was a retrospective seven years observational study based on histomorphological evaluation of 151 ovarian tumours received in department of pathology. Statistical analysis was done and chi-square test was used to see the association. Results: Out of 151 cases, 149 were primary ovarian tumors and two were metastatic tumors to ovary. There were 124 benign tumors, one was borderline and 26 were malignant.Most common age group affected was 31 to 45 years. Benign tumors were common in 16 to 30 years age group, whereas malignant tumors in 46-60 years. For all age group, benign tumors were more common than malignant tumors. Surface epithelial tumors (72.2%) were the most common followed by germ cell tumors (19.9%) and then sex cord stromal tumors (6.6%). Serous cystadenoma (41.93%) was the most common benign tumor followed by mucinous cystadenoma (32.25%). Serous cystadenocarcinoma (38.46%) was the most common malignant tumor. Most common germ cell tumor was mature cystic teratoma (73.3%) and granulosa cell tumor (50%) was the most common sex cord stromal tumor. Conclusion: Diagnosis of neoplastic ovarian lesions requires correlation between clinical, gross and microscopy features as the morphologic diversity of ovarian tumors poses many challenges. In difficult cases, immunohistochemistry and molecular diagnosis may be often required.
Malakoplakia of the gastrointestinal tract is a rare chronic inflammatory disorder, usually affecting the descending colon, sigmoid colon and rectum. It is commonly seen in adults. Only few cases have been reported in children. We report a case of malakoplakia of colon and rectum in a 7-year-old child who presented with multiple polyposis coli.
: The Papanicolaou (Pap) smear used worldwide for cervical screening was developed by Dr George Papanicolaou in 1940s. The Pap smear is a simple, safe and effective test to detect cervical cancer at an early stage.: To study the spectrum of lesions in cervical Pap smear based on The Bethesda System(TBS) 2014 and to determine frequency of premalignant and malignant lesions.: The present prospective study included 200 cases above 20 years of age. The cytological interpretation of smears were made according to TBS 2014. When there was difficulty in differentiating HSIL from other lesions p16 immunostaining was done and evaluated according to the criteria proposed by Wentzensen et al. : Chi – square test was used to see the association between different attributes. Statistical analysis was performed using SPSS version 22. P value <0.05 was considered significant.: The most common lesion was NILM with 175 cases (87.5%) followed by 7(3.5%) SCC, 4(2%) HSIL, 2(1%) cases each of ASCUS, AGC-NOS, LSIL and 1(0.5%) case of ASC-H. Among 200, 7(3.5%) cases were unsatisfactory for evaluation. The subjects were not uniformly distributed (P <0.001). The p16 marker was used in 6(3%) doubtful cases of HSIL among which 2(33.33%) cases were positive. Cervical Pap smear is a useful technique to detect the inflammatory, premalignant and malignant lesions of cervix which helps the clinician to plan further management.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.