Summary.— In 2168 infants, 17 cases of strawberry mark were followed from the earliest neonatal stage. Three angiomata began as telangiectatic lesions surrounded by a pale halo; red puncta then appeared on the dilated vessels. They coalesced and became papular, and red plaques were formed. Three angiomata began as a pale patch; telangiectasia then appeared on this patch. One angioma, first seen as a bruise‐like macule. transformed into a nodular lesion. One angioma began as a simple and uniform erythema and subsequently became nodular. Two infants already showed early haemangiomata at our first examination. In 5 infants, on whom no abnormality was found within the first week of life, a strawberry mark was found later. Two pale patches in the neonatal stage remained abortive angiomata. The haemangiomatous component developed in the majority of cases between the third and fifth weeks of life.
A theoretical assessment has been made on the relationship between the number of channels used and the accuracy of remotely measured sea surface temperature (SST) by multichannel radiance observations from satellite. It has been shown that the accuracy of SST continuously increases with the increase of the number of channels.The accuracy also depends on the accuracy of they clear radiance, accuracy of the initial guess of the SST and transmittance of the atmosphere.A procedure of the objective analysis for the SST has been developed and applied to the analysis of the SST that is obtained in Meteorological Satellite Center (MSC) on routine base from NOAA-6 meteorological satellite. The results has been compared with buoy and ship reports of SST and the GOSSTCOMP sea surface temperature made by NOAA/NESS. Root-mean-square deviation of satellite derived SST from ship reports is about 0.8*K.
OBJECTIVE: This increase on the aneuploidy rate could with the advance of the maternal age could be cause by either an increase of aneuploid embryos per cycle or by a reduction on the absolute number of euploid embryos per cycle. The objective of this study is to ascertain if the source of increase in the rate of aneuploid embryos with advancing maternal age is due to one or the other DESIGN: Retrospective study MATERIALS AND METHODS: Retrospective study of 55,403 embryos from 10,497 cycles from 2013 to 2017, from 126 IVF centers analyzed by Next Generation Sequencing (NGS). Embryos were classified by their diagnosis into: euploid, mosaic, complex mosaic, aneuploid, complex aneuploid, ''mosaic and aneuploid'', and mixed complex. Cycles were distributed in age groups (<35, 35-37, 38-40, 41-42, >42) plus an egg donor group. For each age group, the average and standard deviation of each type of embryo per cycle were obtained.ANOVA analysis was applied to compare the difference ''between'' age groups and ''inside'' age groups for the different types of embryos. Pearson C values were obtained to study the degree of correlation of average number of the different types of embryos with age. RESULTS: The results are summarized in table 1. Euploid and ''mosaics with a euploid'' line showed strong negative correlations with maternal age but aneuploid and ''aneuploid and mosaic'' only showed a mild increase with the bulk of the increase in aneuploidy rates being caused by a decrease in euploid embryos, not an increase in aneuploid ones. CONCLUSIONS: The dramatic decrease in aneuploidy rates is mostly cause by a decrease in euploid embryos, not an increase in aneuploid ones. That is, there are no more aneuploid eggs made or recruited with age but fewer euploid ones, with euploid ones almost exhausted after age 42. The observation that aneuploid embryos are almost constant with age suggest a different causative mechanism than one in which aneuploid embryos would increase with age and euploid ones remain constant or decrease. Mosaics, being post-meiotic are just a fraction of euploid or aneuploid ones, and thus increase or decrease with them.
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