Graphite/SrPdO 3 was utilized for the sensitive determination of some neurotransmitters, namely dopamine (DA), epinephrine (EP), norepinephrine (NE), serotonin (ST), 3,4-dihydroxyphenylacetic acid (DOPAC) and L-dopa. Graphite/SrPdO 3 exhibited higher electrocatalytic activity toward the studied neurotransmitters compared to bare graphite. It was confirmed that graphite electrode was more suitable substrate for immobilization of SrPdO 3 perovskite compared to other surfaces. Moreover, simultaneous determinations of L-dopa, ascorbic acid (AA) and uric acid (UA) or ST were achieved with large peak potential separation. The linear response for L-dopa was obtained in the range of 0.6 μmol L −1 to 9 μmol L −1 with correlation coefficient 0.996 and detection limit 1.63 nmol L −1 . The proposed composite sensor exhibited high reproducibility, enhanced sensitivity, selectivity, anti-interference ability, unique long-term stability (over two months) and applicability in the human urine samples with satisfying results.

No abstract

No abstract

No abstract

No abstract